Oral sustained-release suspension based on a lauryl sulfate salt/complex

24. October 2016

24. October 2016 Abstract The objective of this study was to evaluate the feasibility of lauryl sulfate (LS) salt/complex...

Continuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation, Optimization and Design Space Determination

11. October 2016

The purpose of this work was to increase the solubility and the dissolution rate of itraconazole, which was chosen as...

Investigating the Use of Polymeric Binders in Twin Screw Melt Granulation Process for Improving Compactibility of Drugs

4. September 2016

Traditionally, the melt granulation for pharmaceutical products was performed at low temperature (<90°C) with high-shear granulators using low-melting waxy binders,...

SOLUBILITY AND PERMEATION STUDIES USING SOLUPLUS® AND HPMC WITH A BCS CLASS II AMORPHOUS DRUG

22. August 2016

22. August 2016 Summary of the Master Thesis Indomethacin (IND) is classified in class II of the Biopharmaceutics Classification System...

Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo Pharmacokinetic Studies in Rabbits

21. March 2016

21. March 2016 The aim of the present study was to prepare sublingual delivery systems for sildenafil and evaluate its...

A NEW ENHANCED SORBITOL: CALCIUM DIPHOSPHATE COMPOSITE AS A DIRECT COMPRESSION EXCIPIENT: A COMPARATIVE STUDY

27. February 2016

27. February 2016 Objetive: To evaluate and compared the particle and tableting properties of a new sorbitol (SOR) and anhydrous...

Preparation and evaluation of valsartan by a novel semi-solid self-microemulsifying delivery system using Gelucire® 44/14

17. February 2016

17. February 2016 The aim of the present study was to develop a novel semi-solid self-microemulsifying drug delivery system (SMEDDS)...

13C solid-state NMR analysis of the most common pharmaceutical excipients used in solid drug formulations Part II: CP kinetics and relaxation analysis

22. January 2016

Excipients used in the solid drug formulations differ in their NMR relaxation and 13C cross-polarization (CP) kinetics parameters. Therefore, experimental...

Formulation and Evaluation of Mucoadhesive Thermosensitive in situ Gel of Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis Against HIV

24. December 2015

24. December 2015 Pre-exposure prophylaxis (PrEP) is one of the best preventive strategies in protection against HIV/AIDS. The present research...

Announcement: STEP Database Updated – 29 Excipients now!

8. June 2015

08. June 2015 Announcement: STEP Database Updated – 29 Excipients now! The STEP stands for Safety and Toxicity of Excipients for...

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