Colorcon

The age-related loss of circulating estrogen that occurs during the menopausal transition manifests itself through a variety of symptoms including vasomotor (hot flushes and night sweats), genito-urinary syndrome (vaginal dryness and urinary symptoms), sexual dysfunction, mood, and sleep disturbance…
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Inaugural-Dissertation to obtain the academic degree Doctor rerum naturalium (Dr. rer. nat.) submitted to the Department of Biology, Chemistry, Pharmacy of Freie Universität Berlin by Zun Huang Solubility and dissolution rate are essential for the oral absorption and thus bioavailability of…
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Harleysville, Pennsylvania, USA, 14th October 2021, Colorcon, Inc., a global leader in pharmaceutical film coatings and specialty excipients, today announces the purchase of a majority share in Ideal Cures Pvt. Ltd., a manufacturer of excipients and ready-to-use coating systems for solid oral dosage…
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Minitablets in orodispersible form constitute a flexible drug delivery tool for paediatric and geriatric population as they eliminate the risk of chocking and do not require drinking water in the application. Due to their direct contact with taste buds, taste sensation is an important factor.…
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Spray-dried extracts are prepared as powders or granules after solvent removal, which can be obtained in the presence or absence of pharmaceutical adjuvants. This work aimed to optimize the process of obtaining dried extracts of Peperomia pellucida L. (HBK) by spray drying. The characterization of…
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Modified starches are widely employed excipients in tablets compression. The ability of materials to deform under pressure (compressibility) and create strong compacts (compactability) is then important for tablet manufacture. This study aims to evaluate and compare two partially pregelatinized…
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Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential. The superior physicochemical properties of a recently developed cocrystal of DAP and citric acid (DAP…
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Direct compression (DC) remains the most preferred technique to produce tablets, and its effectiveness is directly influenced by raw material attributes. Therefore, the selection of specific grades of excipients to achieve desirable powder flow and compression properties is of importance. Shifting…
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Thesis findings A solid formulation of a model biopharmaceutical drug (β-galactosidase) was developed and produced by high-speed electrospinning for the first time. A fully aqueous polymeric solution was successfully electrospun with a 30 mL/h feeding rate, which is about 30x higher than the…
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Purpose Drug X is high solubility, high permeability BCS/DCS I small molecule drug. High dose and potential pediatric indication required multiparticulate formulation with not less than 80% drug loading to achieve flexible and low quantity dosing with potential for modified release…
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