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Colorcon
Real-time coating thickness measurement and defect recognition of film coated tablets with machine…
This paper presents a system, where images acquired with a digital camera are coupled with image analysis and deep learning to identify and categorize film coating defects and to measure the film coating thickness of tablets. There were 5 different classes of defective tablets, and the YOLOv5…
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Particle Agglomeration of Acid-Modified Tapioca Starches: Characterization and Use as Direct…
Acid-modified tapioca starches (AMTSs) possessed good compressibility but showed poor particle flowability for preparing tablets by the direct compression method. The aims of this work were to prepare and characterize AMTS agglomerates using polyvinylpyrrolidone (PVP) as an agglomerating agent. The…
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Review on Starter Pellets: Inert and Functional Cores
A significant proportion of pharmaceuticals are now considered multiparticulate systems. Modified-release drug delivery formulations can be designed with engineering precision, and patient-centric dosing can be accomplished relatively easily using multi-unit systems. In many cases, Multiple-Unit…
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Active coating of immediate-release evogliptin tartrate to prepare fixed dose combination tablet…
This study was aimed to develop a fixed dose combination (FDC) tablet containing a low dose of evogliptin tartrate (6.87 mg) for immediate release combined with a high dose (1000 mg) of sustained-release (SR) metformin HCl appropriate for once daily dosing the treatment of type 2 diabetes. To…
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Influence of In Situ Calcium Pectinate Coating on Metoprolol Tartrate Pellets for Controlled Release…
In situ calcium pectinate-coated pellets were proposed by applying an alternate coating method to drug-layered pellets to achieve colon-specific drug delivery. Solution layering of metroprolol tartrate, a water-soluble model drug, on inert core pellets was achieved using a centrifugal granulator…
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Compression Modulus and Apparent Density of Polymeric Excipients during Compression—Impact on…
The present study focuses on the compaction behavior of polymeric excipients during compression in comparison to nonpolymeric excipients and its consequences on commonly used Heckel analysis. Compression analysis at compaction pressures (CPs) from 50 to 500 MPa was performed using a compaction…
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Mucoadhesive Buccal Film of Estradiol for Hormonal Replacement Therapy: Development and In-Vivo…
The age-related loss of circulating estrogen that occurs during the menopausal transition manifests itself through a variety of symptoms including vasomotor (hot flushes and night sweats), genito-urinary syndrome (vaginal dryness and urinary symptoms), sexual dysfunction, mood, and sleep disturbance…
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Development and evaluation of nano-formulations for immediate release oral dosage forms of poorly…
Inaugural-Dissertation to obtain the academic degree Doctor rerum naturalium (Dr. rer. nat.) submitted to the Department of Biology, Chemistry, Pharmacy of Freie Universität Berlin by Zun Huang
Solubility and dissolution rate are essential for the oral absorption and thus bioavailability of…
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Colorcon, Inc. Acquires a Majority Share in Ideal Cures Pvt. Ltd., India
Harleysville, Pennsylvania, USA, 14th October 2021, Colorcon, Inc., a global leader in pharmaceutical film coatings and specialty excipients, today announces the purchase of a majority share in Ideal Cures Pvt. Ltd., a manufacturer of excipients and ready-to-use coating systems for solid oral dosage…
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Utilization of Ethylcellulose Microparticles with Rupatadine Fumarate in Designing Orodispersible…
Minitablets in orodispersible form constitute a flexible drug delivery tool for paediatric and geriatric population as they eliminate the risk of chocking and do not require drinking water in the application. Due to their direct contact with taste buds, taste sensation is an important factor.…
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