Anti-Melanoma Activity of Single Intratumoral Injection of ZnPc Micelles Mixed With in situ Gel in B16 Bearing Mouse

26. October 2023

Photodynamic therapy (PDT) is a potential treatment strategy for melanoma. As a second-generation photosensitizer, Zinc phthalocyanine (ZnPc) has many advantages...

Figure 4. Plasma concentration–time profiles of individual animals dosed with Formulation 5. Formulation 5 = 1 ng/mL is shown as a red dashed line. All values below LLOQ were plotted as ½ LLOQ for illustration purposes.

Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

25. October 2023

Abstract Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but...

A novel cationic arginine-modified Self-Nanoemulsifying drug delivery system (SNEDDS) for improved anticancer and antioxidant activities of Naringin

20. October 2023

Abstract Naringin (NRG) is a flavonoid derived from citrus fruits. Despite its pharmacological significance, NRG's therapeutic effectiveness is constrained by...

Review of the efficacy of nanoparticle-based drug delivery systems for cancer treatment

18. October 2023

This review evaluates the literature on nanoparticle-based drug delivery systems for cancer treatment and assesses their efficacy. Nanoparticles have shown...

Figure (1): Saturated solubility of PA in different oils.

Preparation and Characterization of Prednisolone Acetate Microemulsion for Ophthalmic Use

17. October 2023

Abstract Background: Prednisolone acetate is an ester form of prednisolone. It is used topically as an ophthalmic suspension to treat many inflammatory...

Enhanced Anti-Herpetic Activity of Valacyclovir Loaded in Sulfobutyl-ether-β-cyclodextrin-decorated Chitosan Nanodroplets

16. October 2023

Valacyclovir (VACV) was developed as a prodrug of the most common anti-herpetic drug Acyclovir (ACV), aiming to enhance its bioavailability....

Structural modifications for the conversion of proteins and peptides into stable dried powder formulations: A review

10. October 2023

The drying of biomolecules into powdered formulations has become the main form of long-term product stabilisation, allowing for the delivery...

Tioconazole-Loaded Transethosomal Gel Using Box–Behnken Design for Topical Applications: In Vitro, In Vivo, and Molecular Docking Approaches

7. October 2023

Tioconazole (TCZ) is a broad-spectrum fungicidal BCS class II drug with reported activity against Candida albicans, dermatophytes, and certain Staphylococci bacteria. We report the...

Design and development of donepezil hydrochloride loaded nanostructured lipid carriers for efficient management of Alzheimer’s disease

5. October 2023

Objective The primary objective of this study was to develop nanostructured lipid carriers of donepezil hydrochloride (DNZ HCl) for effective...

CPHI Barcelona 2023 – with a focus on excipients

5. October 2023

This year CPHI Europe opens its doors in Barcelona at Fira Barcelona Gran Via. From 24th to 26th October you...

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