DFE Pharma

Abstract Purpose To overcome the strong inter-particulate interactions between the drug and carrier in dry powder inhalers (DPIs), an amorphous...

Abstract Objectives: A customizable 3D-bioprinted core-in-shell platform was developed for time-dependent oral colon delivery of live microorganisms. The system conveyed Lacticaseibacillus paracasei as...

Abstract Background/Objectives: The objective of this study was to design and optimize a continuous wet granulation process for Amiodarone hydrochloride...

Abstract This research evaluated the viability of powder discharge-based KinetiSol (pKSD) as a rapid, solvent-free particle engineering technology for producing...

Abstract Objectives This study aims to investigate the effect of compaction pressure, coating polymer, pellet core, and spatial arrangement on...

Abstract Roller compaction is a widely applied dry granulation technique in the pharmaceutical and food industries, valued for its scalability,...

Abstract Background/Objectives: Accurate determination of active pharmaceutical ingredient (API) particle size within dry powder inhaler (DPI) formulations is essential for ensuring...

Abstract Purpose This research was designed to systematically investigate the performance of three lactose-based co-processed excipients (CPEs): SuperTab® 40LL, StarLac®, and...

Abstract Bulk density (ρb) serves as a fundamental powder parameter across various industries. In the pharmaceutical industry, its implications on...

Abstract Environmental relative humidity (RH) and temperature (T) are known to be promoters of physicochemical changes in pharmaceutical grade lactose,...