Spherical agglomerates of lactose as potential carriers for inhalation

29. December 2020

We report here on spherical lactose agglomerates as potential carriers for inhalation applications. Micromeritic properties of three spherical lactose agglomerates...

$Roll Compactor with In-line laser diffraction to measure granule size$

Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width

22. December 2020

In continuous manufacturing of pharmaceuticals, dry granulation is of interest because of its large throughput capacity and energy efficiency. In...

3D Printing in Pharma with Lactose

14. December 2020

3D printing brings a whole new dimension to Lactose Are you ready for the future? 3D Powder bed printing enables...

Rapid releasing naproxen Liqui-Pellet using effervescent agent and neusilin US2

3. December 2020

Objective(s): Liqui-Mass technology has shown promising advantages in terms of commercial production and formulation manipulation. This study attempts to further...

Hopper design for piezo-actuated granular flow in powder bed 3D food printing

27. November 2020

The flow properties of powders in hoppers are studied in order to make a design procedure for piezo-actuated hoppers that...

Data-smart machine learning methods for predicting composition-dependent Young’s modulus of pharmaceutical compacts

12. November 2020

The ability to predict mechanical properties of compacted powder blends of Active Pharmaceutical Ingredients (API) and excipients solely from component...

3D-printing of lopinavir printlets by selective laser sintering and quantification of crystalline fraction by XRPD-chemometric models

12. November 2020

The objectives of this study were to develop and characterize amorphous lopinavir (LPV) printlets and to the quantify crystalline fraction...

Insights into the Moisture Scavenging Properties of Different Types of Starch in Tablets Containing a Moisture-Sensitive Drug

10. November 2020

Starch is a commonly used excipient in the pharmaceutical industry. However, information on the effect of the moisture scavenging properties...

The relevance of granule fragmentation on reduced tabletability of granules from ductile or brittle materials produced by roll compaction/dry granulation

6. November 2020

Roll compaction/dry granulation often results in loss of tabletability. The two main hypotheses for this are granule hardening and granule...

Co-administration of mini-tablets orlistat and xanthan gum

Anti-obesity effect with reduced adverse effect of the co-administration of mini-tablets containing orlistat and mini-tablets containing xanthan gum: In vitro and in vivo evaluation

28. October 2020

The purpose of this study was to develop an oral dosage form of orlistat for the treatment of obesity with...

DFE Pharma