DFE Pharma

Abstract The flowability and compressibility of powders during tableting are crucial for determining the quality of pharmaceutical products. Although silicon...

Abstract Since the FDA approval of the first nanodrug Doxil® in 1995, twenty subsequent liposome-and lipid nanoparticle (LNP) based drugs...

This poster was presented at the ECP 2025 in Porto   A proof of concept with wet extrusion Introduction Veterinary...

The effect of binder types on the granule properties and tablet quality for high shear wet granulation and tableting (HSWG-T)...

The mixing of ductile lubricant particles is known to have several negative effects on tablet properties, such as decreased hardness...

Purpose Understanding batch-to-batch variation of excipients and correlating this to process performance is a key concept of Quality-by-Design for pharmaceutical...

The pharmaceutical industry has been shifting towards continuous manufacturing, specifically for tablet production. Compared to batch processing, continuous tableting exhibits...

Abstract Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher desired drug substance concentrations....

Abstract This study explores the potential of spectroscopic analysis combined with Partial Least Squares Regression (PLS) and Multivariate Curve Resolution-Alternating...

Abstract We propose a novel approach for predicting the solid fraction after roller compaction processes. It is crucial to predict...