Methodology for rapid development of a continuous loss-in-weight feeding process

18. March 2025

The pharmaceutical industry has been shifting towards continuous manufacturing, specifically for tablet production. Compared to batch processing, continuous tableting exhibits...

Machine learning driven acceleration of biopharmaceutical formulation development using Excipient Prediction Software (ExPreSo)

11. March 2025

Abstract Formulation development of protein biopharmaceuticals has become increasingly challenging due to new modalities and higher desired drug substance concentrations....

Quantification of Antibiotics in Multicomponent Drug Formulations using UV-Vis Spectrometer with PLS and MCR-ALS

6. March 2025

Abstract This study explores the potential of spectroscopic analysis combined with Partial Least Squares Regression (PLS) and Multivariate Curve Resolution-Alternating...

$Scale-independent solid fraction prediction in dry granulation process using a gray-box model integrating machine learning model and Johanson model$

Scale-independent solid fraction prediction in dry granulation process using a gray-box model integrating machine learning model and Johanson model

5. March 2025

Abstract We propose a novel approach for predicting the solid fraction after roller compaction processes. It is crucial to predict...

Development of tablet formulations containing genistein solid dispersion optimized using Box-Behnken design for enhanced solubility

3. March 2025

Abstract Genistein, a bioactive isoflavone, offers therapeutic potential but is hindered by poor water solubility, limiting its oral bioavailability. This...

DFE Pharma