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Galvita
Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine…
Abstract
Ayahuasca, a traditional psychoactive Amazonian brew, usually contains N,N-dimethyltryptamine (DMT) and β-carboline (harmine, harmaline, tetrahydroharmine) monoamine oxidase inhibitors. However, the pharmacological interactions between these compounds remain incompletely understood. In…
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Photo and video recap Pharma Excipients @CPHI Milan 2024
This year´s CPHI Europe happend last week from 8th to 10th October in Milano at Fiera Milano.
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Pharma Excipients visited the excipients hall, hall 6 for you and in the following you find a broad range of booth photos as well as short introduction videos we recorded at CPhI 2024 in Milan.
Here…
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Pharmacometrics to Evaluate Dosing of the Patient-Friendly Ivermectin CHILD-IVITAB in Children ≥ 15…
Abstract
The antiparasitic drug ivermectin is approved for persons > 15 kg in the US and EU. A pharmacometric (PMX) population model with clinical PK data was developed (i) to characterize the effect of the patient-friendly ivermectin formulation CHILD-IVITAB on the absorption process and (ii)…
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Calcium phosphate microcapsules for paediatric drug delivery
This poster was presented by Galvita at EuPFI 2024 in Rotterdam
Introduction
Modern drug delivery needs to use novel multifunctional materials for developing medicinal products and new therapies. Porous particles attract a lot of attention as promising drug delivery systems. Functions of porous…
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CPHI Milan 2024 – with a focus on excipients
This year CPHI Europe opens its doors in Milano at Fiera Milano.
From 8th to 10th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack,
P-MEC, FDF, ICSE, MedTech and BioProduction will be held together with CPHI.
Pharma Excipients gives you an overview…
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Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced…
Abstract
Ivermectin has been used since the 1980s as an anthelmintic and antiectoparasite agent worldwide. Currently, the only available oral formulation is tablets designed for adult patients. A patient-friendly orodispersible tablet formulation designed for pediatric use (CHILD-IVITAB) has been…
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Calcium Phosphate Microcapsules as Multifunctional Drug Delivery Devices
Abstract
More challenging active pharmaceutical ingredients are entering the market, spurring the introduction of novel drug delivery strategies that necessitate a paradigm shift from exhausted excipients to materials with combined actions and multiple functionalities. In this study, an inorganic…
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Meeting Challenges of Pediatric Drug Delivery: The Potential of Orally Fast Disintegrating Tablets…
A majority of therapeutics are not available as suitable dosage forms for administration to pediatric patients. The first part of this review provides an overview of clinical and technological challenges and opportunities in the development of child-friendly dosage forms such as taste masking,…
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