PMC Isochem

A solid self-emulsifying drug delivery system (SEDDS) of paclitaxel (PTX) was developed that could enhance its oral bioavailability and neutralize...

A significant proportion of new API’s in development are poorly soluble and require alternative formulation approaches to achieve adequate oral...

Topical ocular delivery of therapeutics are always a challenging arena in order to achieve high ocular bioavailability with safe administration....

Curcumin (CUR), a non-toxic natural compound with potent antitumor activity, was limited in clinical application due to its insolubility and...

Plant-derived phenolic compounds have multiple positive health effects for humans attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc. These...

Among all types of cancer encountered in women, breast cancer is the most prevalent, with the highest mortality rate. An...

The nature of the interaction of bile salt micelles with exogenous surfactants used in formulations and the consequent impact on...

Nimodipine (NMD), a calcium channel blocker, has demonstrated benefits in treating glaucoma. However, its ocular therapeutic application remains limited due...

Cancer is considered as one of the biggest threats to human worldwide. Researchers suggest that tumour is not just a...

Amorphous solid dispersion (ASD) is commonly used in pharmaceutical industry. It has been mainly employed to enhance the oral bioavailability...