Shin-Etsu

Abstract Ternary co-amorphous systems, comprising a drug, a low molecular weight co-former, and a polymer, are a promising approach to...

Abstract The solubility behavior of drugs is a critical factor in formulation development. Approximately 40–45% of new drugs face market...

The mixing of ductile lubricant particles is known to have several negative effects on tablet properties, such as decreased hardness...

Abstract A tunable modular design (TMD) as a new approach was proposed to tailor the dose and drug release profile...

Abstract In this study, an artificial intelligence-based machine vision system was developed for in-line particle size analysis during the pellet...

Abstract It is desirable but remains challenging to develop high drug load amorphous solid dispersions (ASDs) without compromising their quality...

Abstract Pediatric treatment of brain-related diseases often requires oral medications, where palatability is crucial for patient adherence and therapeutic success....

Abstract Moisture sensitivity poses a challenge in formulating oral dosage forms, particularly when considering disintegrants’ swelling due to prior moisture...

Abstract Enzalutamide (ENZ), marketed under the brand name Xtandi® as a soft capsule, is an androgen receptor signaling inhibitor drug actively...

Abstract Currently, most amorphous solid dispersion (ASD) formulations contain a single polymer to stabilize an amorphous drug. However, a single...