SPI Pharma

In this study, insights into the development and optimization of a co-processed excipient based on mesoporous silica are presented. The...

Particle breakage by attrition is unavoidable in some unit operations and can lead to uncontrolled behavior of materials during processing....

Repaglinide (RPG), a monotherapy insulin secretagogue used to treat diabetes mellitus-type II yet, it suffers from poor water solubility and...

Expert System for Drug Development, i.e. SeDeM Expert System (Span. Sistema Experto para DEsarrollo de Medicamentos) represents a method intended...

Orally disintegrating tablets are an emerging trend in novel drug delivery system and have received ever increasing demand during the...

Understanding the tabletability change of materials after granulation is critical for the formulation and process design in tablet development. In...

Introduction Oral disintegrating tablets (ODTs) are patient-centric drug delivery systems (for example, for pediatrics, geriatrics, and psychiatric patients with dysphagia)...

The selection of appropriate functional co-processed excipient (CPE) is a crucial stage in orodispersible minitablets (ODMTs) development. This paper aimed...

Palatability and patient acceptability are critical attributes of dispersible tablet formulation. Co-processed excipients could provide improved organoleptic profile due to...

Tableting by direct compression (DC) is one of the simplest and most cost-effective drug manufacturing approaches. However, most active pharmaceutical...