Using a Material Library to Understand the Change of Tabletability by High Shear Wet Granulation

4. December 2022

Understanding the tabletability change of materials after granulation is critical for the formulation and process design in tablet development. In...

Why Oral Disintegrating Tablets - by Roquette

Oral Disintegrating Tablets – see the solution landscape

1. November 2022

Introduction Oral disintegrating tablets (ODTs) are patient-centric drug delivery systems (for example, for pediatrics, geriatrics, and psychiatric patients with dysphagia)...

Impact of co-processed excipient particles solidity and circularity on critical quality attributes of orodispersible minitablets

6. April 2021

The selection of appropriate functional co-processed excipient (CPE) is a crucial stage in orodispersible minitablets (ODMTs) development. This paper aimed...

Co-Processed Excipients for Dispersible Tablets—Part 2: Patient Acceptability

11. February 2021

Palatability and patient acceptability are critical attributes of dispersible tablet formulation. Co-processed excipients could provide improved organoleptic profile due to...

Unit operations employed in the production of tablets via granulation or spray:co-spray drying

Spray Drying for Direct Compression of Pharmaceuticals

8. February 2021

Tableting by direct compression (DC) is one of the simplest and most cost-effective drug manufacturing approaches. However, most active pharmaceutical...

Co-Processed Excipients for Dispersible Tablets–Part 1: Manufacturability

8. February 2021

Co-processed excipients may enhance functionality and reduce drawbacks of traditional excipients for the manufacture of tablets on a commercial scale....

Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation

6. January 2021

Diacerein (DCN), a potent anti-inflammatory API used to treat osteoarthritis yet, it suffers from poor water solubility which affects its...

Pilot-scale high-speed electrospinning device with a continuous cyclone sample collector

Pharmaceutical applications of aqueous scaled-up electrospinning

14. December 2020

Thesis findings A solid formulation of a model biopharmaceutical drug (β-galactosidase) was developed and produced by high-speed electrospinning for the...

Tablet properties of pre- and post-storage tablets consisting of different mannitol grades

Effect of Different Direct Compaction Grades of Mannitol on the Storage Stability of Tablet Properties Investigated Using a Kohonen Self-Organizing Map and Elastic Net Regression Model

24. September 2020

This study tested 15 direct compaction grades to identify the contribution of different grades of mannitol to the storage stability...

Fexofenadine hydrochloride orally disintegrating tablets for pediatric use

17. October 2017

17. October 2017 Allergic rhinitis is a common disease in children which has considerable negative effects on the quality of...

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