Nanoscale investigation of human skin and study of skin penetration of Janus nanoparticles

10. March 2020

Janus nanoparticles (JNP) are innovative nanocarriers with an interesting pharmaceutical and cosmetic potential. They are characterized by the presence of...

Gellan gum and its methacrylated derivatives as in situ gelling mucoadhesive formulations of pilocarpine: In vitro and in vivo studies

21. February 2020

Gellan gum was chemically modified by the reaction with methacrylic anhydride to produce derivatives with 6, 14 and 49% methacrylation....

The structure of resveratrol. Adapted from © Karl Harrison 3DChem.com

Novel Nanocarriers for Targeted Topical Skin Delivery of the Antioxidant Resveratrol

14. February 2020

Resveratrol (RSV) is a potent lipophilic antioxidant with a low aqueous solubility. Novel nanoformulations have been successfully developed and evaluated...

Design, Optimization and Characterization of Nanostructured Lipid Carriers of Raloxifene Hydrochloride for Transdermal Delivery

10. February 2020

Raloxifene Hydrochloride (RXL), a BCS class II drug, is used for the treatment of invasive breast cancer and osteoporosis in...

Chitosan oligosaccharide enhances binding of nanostructured lipid carriers to ocular mucins: Effect on ocular disposition

3. February 2020

The objective of the study was to assess the effect of enhanced mucoadhesion of a cationic mucoadhesive nanostructured lipid carrier...

Formulation, optimization and in vitro evaluation of nanostructured lipid carriers for topical delivery of apremilast

20. January 2020

This work was aimed to formulate topical Apremilast loaded nanostructured lipid-carriers (NLCs) for the management of psoriasis. Psoriasis is a...

Montelukast Nanocrystals for Transdermal Delivery with Improved Chemical Stability

29. December 2019

A novel nanocrystal system of montelukast (MTK) was designed to improve the transdermal delivery, while ensuring chemical stability of the...

Mechanistic Evaluation of Enhanced Curcumin Delivery through Human Skin In Vitro from Optimised Nanoemulsion Formulations Fabricated with Different Penetration Enhancers

10. December 2019

Curcumin is a natural product with chemopreventive and other properties that are potentially useful in treating skin diseases, including psoriasis...

Bacillus licheniformis levan as a functional biopolymer in topical drug dosage forms: From basic colloidal considerations to actual pharmaceutical application

1. December 2019

In this study, the abilities of hydroxypropyl methylcellulose (HPMC) and methylcellulose (MC) as nonionic surfactants to improve the dissolution rate...

Novel in situ gelling ophthalmic drug delivery system based on gellan gum and hydroxyethylcellulose

14. November 2019

Achieving drug delivery at the ocular level encounters many challenges and obstacles. In situ gelling delivery systems are now widely...

Topical Excipient

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→ Introduction to Topical Excipients