Bioavailability enhancement

Abstract Background/Objectives: The ABCG2 transporter actively effluxes anticancer drugs, reducing their efficacy and promoting multidrug resistance (MDR). Developing oral formulations...

Abstract Introduction This study explores the emulsification behavior and oral delivery performance of dry and wet inverted lipid phases (ILPdry and...

Abstract The limited aqueous solubility of numerous active pharmaceutical ingredients (APIs) remains a major barrier to achieving optimal oral bioavailability,...

  Lipid excipients offer a unique combination of benefits Poor solubility, poor permeability, and pre-systemic elimination are factors that can...

Abstract The present study aimed to design, optimize, and evaluate enteric-coated nanocarriers to enhance the oral bioavailability of Rifaximin, a...

Abstract Endometriosis (EM) is a gynaecological disorder for which drug combinations such as atorvastatin (ATV) and silybin (SB) hold therapeutic...

Abstract Pramipexole dihydrochloride (PPX) is a Biopharmaceutical Classification System (BCS) Class I drug with a short half-life, and its aqueous...

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers See the new book, edited by Rajendra Awasthi, Santosh Kumar Singh,...

Abstract This study investigates the influence of phospholipid saturation by comparing hydrogenated soy phosphatidylcholine (HSPC) and egg yolk phosphatidylcholine (EPC)...

Abstract For any drug to be therapeutically efficacious it must enter the systemic circulation and in order to do so,...