Cyclodextrin complexation studies as the first step for repurposing of chlorpromazine

12. May 2020

The antipsychotic drug chlorpromazine (CPZ) has potential for the treatment of acute myeloid leukemia, if central nervous system side-effects resulting...

Modified cyclodextrins as broad-spectrum antivirals

11. May 2020

Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that irreversibly inhibit viruses (virucidal) are postulated...

Microneedle array delivered recombinant coronavirus vaccines - Immunogenicity and rapid translational development

Combating Coronavirus: Key Role of Cyclodextrins in Treatment and Prevention

10. May 2020

A new strain of coronavirus (2019-nCoV) started to emerge in late December 2019 from Wuhan, the capital of Hubei Province...

Combating Coronavirus: Key Role of Cyclodextrins in Treatment and Prevention

10. May 2020

A new strain of coronavirus (2019-nCoV) started to emerge in late December 2019 from Wuhan, the capital of Hubei Province...

Microwave-assisted β-cyclodextrin/chrysin inclusion complexation: An economical and green strategy for enhanced hemocompatibility and chemosensitivity in vitro

6. May 2020

Highlights • 1:1 solid inclusion complex (IC) of chrysin with β-cyclodextrin prepared. • Microwave irradiation method is time-saving and environmentally...

Common formulation strategies to improve API solubility for solid oral dosage forms

Factors affecting the stability and performance of amorphous solid dispersions of poorly soluble active pharmaceutical ingredients

29. April 2020

Over the last twenty years, the poor solubility profile of pipeline drugs has limited their development as solid oral dosage...

Oral tablet formulations containing cyclodextrin complexes of poorly water soluble cefdinir to enhance its bioavailability

18. April 2020

Cefdinir (CFD) is an oral cephalosporin antibiotic commonly used in the treatment of community-acquired infections. The oral bioavailability of CFD...

Mechanochemical activation with cyclodextrins followed by compaction as an effective approach to improving dissolution of rutin

8. April 2020

Rutin is one of the most important flavonoids with poor bioavailability. This work aimed at addressing the issue of poor...

Polypseudorotaxanes of Pluronic® F127 with Combinations of α- and β-Cyclodextrins for Topical Formulation of Acyclovir

2. April 2020

Acyclovir (ACV) is one of the most used antiviral drugs for the treatment of herpes simplex virus infections and other...

Cyclodextrin Based Nanoparticles for Drug Delivery and Theranostics

22. March 2020

Colloidal nanoparticulate technology has been described in the literature as a versatile drug delivery system. But it possesses some inherent...

Cyclodextrin