formulation

Cyclodextrins (CDs) are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits linked by α-1,4 glycosidic...

This work aimed to optimize a celecoxib (CXB)-loaded solid lipid nanoparticles (SLN) colon delivery system for the enhancement of anticancer...

Drug overdose connected to marketed pharmaceutical products, particularly opioids, occurs at an alarming rate. Novel strategies through innovative formulation approaches that...

Die filling is a critical step in the pharmaceutical tableting process as it determines the uniformity in tablet weight, which...

Proteins, the building blocks of life, are increasingly being used as therapeutics for treating several diseases. Yet, there are challenges...

The efficient development of robust tableting processes is challenging due to the lack of mechanistic understanding on the impact of...

Predicting tablet defects, such as capping, that might occur during manufacturing, is a challenge in the pharmaceutical industry. In the...

Amorphous solid dispersions (ASDs) have gained attention as a formulation strategy in recent years, with the potential to improve the...

Mechanistic process modeling presents an opportunity to reduce experimental burden, enabling relationships between process parameters and product attributes to be...

In this study, a hybrid modeling framework was developed for predicting size distribution and content uniformity of granules in a...