Gelatin is a versatile and widely used ingredient in the pharmaceutical industry, where it serves various critical functions in the formulation and production of pharmaceutical products. This article explores the sources, manufacturing process, and applications of pharmaceutical gelatin, shedding light on its significance in pharmaceuticals.
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Gelatin
Mastering the Softgel Encapsulation Process: A Deep Dive into Precision Manufacturing
Softgel capsules are a cornerstone of modern pharmaceutical and nutraceutical industries, offering consumers a seamless, easy-to-swallow solution that enhances bioavailability and ensures precise dosing. This article will examine the intricate processes involved in softgel encapsulation,…
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Development and Evaluation of Lactose-Free Single-Unit and Multiple-Unit Preparations of a BCS Class…
Abstract
Background/Objectives: The aim of the present study was to develop lactose-free formulations of rivaroxaban, a novel oral anticoagulant used for the treatment and prevention of blood clotting. As a BCS Class II drug, rivaroxaban is characterized by poor solubility in aqueous media, posing…
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Evaluation of physical and chemical modifications to drug reservoirs for stimuli-responsive…
Abstract
Hydrogel-forming microneedle (MN) arrays are minimally-invasive devices that can penetrate the stratum corneum, the main barrier to topical drug application, without causing pain. However, drug delivery using hydrogel-forming MN arrays tends to be relatively slow compared to rapid drug…
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Effect of Encapsulation of Lactobacillus casei in Alginate–Tapioca Flour Microspheres Coated with…
To realize the health benefits of probiotic bacteria, they must withstand processing and storage conditions and remain viable after use. The encapsulation of these probiotics in the form of microspheres containing tapioca flour as a prebiotic and vehicle component in their structure or shell affords…
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Microneedle patch casting using a micromachined carbon master for enhanced drug delivery
For successful treatment of diseases, sufficient therapeutics must be provided to the body. Microneedle applications in therapeutic delivery and analytics sampling are restricted because of various issues, including smaller area for drug loading and analytics sampling. To achieve sufficient drug…
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Transdermal delivery of bisphosphonates using dissolving and hydrogel-forming microarray patches:…
Abstract
As of 2023, more than 200 million people worldwide are living with osteoporosis. Oral bisphosphonates (BPs) are the primary treatment but can cause gastrointestinal (GI) side effects, reducing patient compliance. Microarray (MAP) technology has the potential to overcome GI irritation by…
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Development of quercetin-loaded electrospun nanofibers through shellac coating on gelatin:…
Quercetin possesses multiple biological activities. To achieve efficient colon-specific release of quercetin, new composite nanofibers were developed by coating pH-responsive shellac on hydrophilic gelatin through coaxial electrospinning. These composite nanofibers contained bead-like structures.…
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Advanced Delivery Strategies of Nintedanib for Lung Disorders and Beyond: A Comprehensive Review
Nintedanib, a primary treatment for lung fibrosis, has gathered substantial attention due to its multifaceted potential. A tyrosine kinase inhibitor, nintedanib, inhibits multiple signalling receptors, including endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor…
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The Art Of Soft Gelatin Capsule Shells: A Look Into The Manufacturing Process
Learn the step-by-step process of gelatin production, from raw material preparation to the final product. This guide covers both the hot melt and cold melt methods, equipment needed, and common issues encountered in the manufacturing process.
Production of Gelatin
The production of gelatin for…
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Gelatin Shell Material and Formulations for Softgels: An In-Depth Guide
Gelatin, a versatile protein derived from animal sources, is crucial in producing softgel capsules. Known for its ability to form gels in aqueous solutions, gelatin provides the perfect medium for encapsulating various substances. This comprehensive guide will explore the different aspects of…
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