Gelatin is a versatile and widely used ingredient in the pharmaceutical industry, where it serves various critical functions in the formulation and production of pharmaceutical products. This article explores the sources, manufacturing process, and applications of pharmaceutical gelatin, shedding light on its significance in pharmaceuticals.
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Gelatin
A bigel co-delivering highly hydrophilic and hydrophobic natural compounds for enhanced ulcerative…
Abstract
Bigel, formed by high-speed shearing of hydrogel and oleogel, is suited to deliver both lipophilic and hydrophilic active compounds. patchouli oil and paeoniflorin, despite their potential in treating ulcerative colitis, face challenges due to patchouli oil’s poor aqueous solubility and…
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Clinical implementation of a paediatric 3D-printed combination of Sulfamethoxazole and Trimethoprim
Abstract
Adherence to treatment is one of the major challenges in chronic diseases. Inappropriate dosage forms or bad taste are the main factor for non-adherence, especially in paediatric patients. 3D printed medicines could be tailored to specific patients to make medicines more acceptable,…
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Biological applications on a novel composite hydrogel containing mesoporous silica nanoparticles…
Abstract
Polymer nanocomposites have prolific applications in the environmental and health domain. Healthcare workers have constantly faced a challenge in constructing an effective sustained-release system for drugs, especially in areas where it is difficult to follow traditional treatment…
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Development and optimization of lyophilized dry emulsion tablet for improved oral delivery of…
Abstract
Ivermectin (IVM) is a widely used antiparasitic agent and has been repurposed for the treatment of COVID-19. However, its poor water solubility and low bioavailability present significant challenges, often requiring large doses for therapeutic effectiveness. This poses a burden on…
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Foam-Based Drug Delivery Systems for Skin Disorders: A Comprehensive Review
Abstract
Foam-based drug delivery systems signify a significant innovation in dermatology, facilitating improved drug penetration and administration via a gas-liquid dispersion matrix. These formulations have shown considerable promise in the medical, cosmetic, and pharmaceutical fields. Recent…
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The Future of Medicine: How 3D Printing Is Transforming Pharmaceuticals
Abstract
Three-dimensional printing technology is transforming pharmaceutical manufacturing by shifting from conventional mass production to additive manufacturing, with a strong emphasis on personalized medicine. The integration of bioinks and AI-driven optimization is further enhancing this…
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Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges
Abstract
The field of three dimensional (3D) bioprinting has witnessed significant advancements, with bioinks playing a crucial
role in enabling the fabrication of complex tissue constructs. This review explores the innovative bioinks that are
currently shaping the future of 3D bioprinting,…
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Salcaprozate-based ionic liquids for GLP-1 gastric delivery: A mechanistic understanding of in vivo…
Abstract
Oral delivery of peptides requires formulations with high concentrations of permeation enhancer (PE) to promote absorption, and often necessitates fasting time between dosing and food ingestion. Improved formulations promoting a more rapid absorption would increase convenience of use but…
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Personalized Medicine Through Semisolid-Extrusion Based 3D Printing: Dual-Drug Loaded Gummies for…
Abstract
Purpose
The purpose of this research was to develop and characterize dual-drug Isoniazid-Pyridoxine gummies using Semisolid Extrusion (SSE) 3D printing technology, aimed at personalized dosing for a broad patient demographic, from pediatric to geriatric. This study leverages SSE 3D…
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Formation of water-in-water emulsions and microgels in nonionic surfactant + gelatin aqueous…
Abstract
Hypothesis
Water-in-water (W/W) emulsions can be obtained when two water-soluble components are mutually immiscible. The scientific literature on W/W emulsions focuses on polymer–polymer mixtures, with only a few reports on polymer-salt systems, and no documented cases involving…
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