Hot-melt extrusion

The long-term use of benzodiazepine receptor agonists (BZRAs) is associated with multiple side effects, such as increased sedation, hangover or...

Using discrete element method (DEM) modeling and near-infrared (NIR) spectroscopy, the feasibility of powder mixing in the initial pre-melting zones...

Looking to enhance the solubility of poorly soluble drugs? Consider AFFINISOL™, a water-soluble polymer that optimizes solubility enhancement by maintaining...

The aim of this research was to study the impact of melting and quenching approach on solid-state characteristics of amorphous...

Three dimensional (3D) printing as an advanced manufacturing technology is progressing to be established in the pharmaceutical industry to overcome...

Eudragit® polymers are polymethacrylates highly used in pharmaceutics for the development of modified drug delivery systems. They are widely known due...

Background Fixed dose combination (FDC) products are common in the treatment of various disease such as hypertension, diabetes, HIV and...

Purpose Solid dispersions formulations manufactured by Hot-Melt-Extrusion (HME) have shown to improve drug release for BCS class II drugs, such...

The current study is aimed at the development of chrono modulated multiple unit particulate systems (MUPS) of nifedipine (ND) by...

A variety of polymer:polymer blends was used to prepare hot melt extrudates and empty capsules (bodies and caps) by injection molding...