Hot-melt extrusion

06. November 2017 Abstract The aim of this study was to improve the pharmaceutical properties of theobromine (TB), particularly its...

31. August 2017 This work aimed to obtain an optimized itraconazole (ITZ) solid oral formulation in terms of palatability and...

28. July 2017 Abstract The objective of the current study was to develop an amorphous solid dispersion for a high...

31. March 2017 The majority of today’s new chemical entities are poorly water-soluble. One widely used means of overcoming that...

Abstract In the present study, we aimed to prepare a gastroretentive drug delivery system that would be both highly resistant...

Abstract It is often challenging to precisely manipulate the release behavior of hydrophilic drugs that is believed to be crucial...

Abstract Thermal processing technologies continue to gain interest in pharmaceutical manufacturing. However, the types and grades of polymers that can...

15. December 2016 Abstract Solid dispersion formulations made of itraconazole (ITZ) and Soluplus® (polyethylene glycol, polyvinyl acetate and polyvinylcaprolactame-based graft...

The purpose of this work was to increase the solubility and the dissolution rate of itraconazole, which was chosen as...