Magnesium Stearate

Tableting of biomolecules is a challenging formulation phase due to their sensitivity to various process parameters, such as compression pressure,...

The thermodynamic analysis of tablet formation includes the thermal and mechanical analysis during compression. The aim of this study was...

Polymeric amorphous solid dispersion (ASD) is a popular approach for enhancing the solubility of poorly water-soluble drugs. However, achieving both...

This study investigates the feasibility of a compaction simulator and oscillating mill to mimic a roller compactor as a material...

The manufacture of medicines on demand for a particular patient, at the point of care, may be achieved via 3D...

The use of physiologically based biopharmaceutics modeling (PBBM) and bioequivalence safe space is increasingly common for immediate-release drug products. However,...

This exploratory study investigated the minimum required Raman mapping area for predicting sustained-release tablet dissolution profiles based on intra-tablet homogeneity....

Hot-melt extrusion is a well-established tool in the pharmaceutical industry, mostly implemented to increase the solubility of poorly soluble drugs....

In this study, insights into the development and optimization of a co-processed excipient based on mesoporous silica are presented. The...

Abstract Risk control for nitrosamine impurities in drug products is currently a major challenge in the industry. Nitrosamines can form...