Mannitol

Fixed-dose combination (FDC) products containing at least two different active pharmaceutical ingredients are designed to treat more effectively different pathologies...

This study provides the results of investigation on scaling approaches for three differently-sized continuous granulation lines, each consisting of a...

Felodipine (FLD), a dihydropyridine calcium channel blocker with excellent antihypertensive effect, is poorly soluble and undergoes extensive hepatic metabolism, which...

Diabetes is characterized by chronic hyperglycemia. Although metformin hydrochloride (MHCl)- and glyburide (GLB)-containing conventional tablets are available in the market...

Sensitivity to a stress concentration is important for the development of pharmaceutical tablets as it is related to defects like...

Twin screw granulation is becoming increasingly relevant due to its compact size, continuous and robust mode of operation, customizable design,...

Phage therapy has gained prominence due to the increasing pathogenicity of “super bugs” and the rise of their multidrug resistance...

The aim of this research was to simulate oral pharmacokinetic (PK) profiles of atorvastatin from orally disintegrating tablets (ODTs) dosed...

Isomalt is a polyol derived from sucrose. Advantages of this excipient are its sweet taste, which is supposed to allow...

Calcitriol, as the biologically active form of vitamin D3, is essential for patients with renal osteopathy. The solubilization, stabilization, and...