Herbal based medicines are used for the treatment of many diseases from ancient times while

pharmaceutical chemistry is recently developed. Usually Herbal medicines have been delivered orally in both animals and human. Targeted drug-delivery systems currently more common for the treatment of most life threatening diseases such as cancers. In addition to drug eluting devices many nano based devices delivering active pharmaceutical ingredients or herbal based extracts or particles are growing in demand and they have been approved by FDA and other regulatory bodies. This mini review intends to overview role of nanofibers for the delivery of herbal ingredients and natural plant based extract for the biomedical applications.