Pharma Excipients

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Development of a stability indicating high-performance liquid chromatography method for determination of cenobamate: study of basic degradation kinetics

Abstract This study presents a stability indicating high-performance liquid chromatography HPLC method for the determination of cenobamate (CNB) in presence of its main impurity (CNB H-impurity) and degradation products. The chromatographic separation was carried out on a Thermo BDS Hypersil-C18 column (150 × 4.6 mm; 5 μm) with a mobile phase…