Ocular Drug Delivery: a Comprehensive Review

25. February 2023

The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted...

Research progress of ophthalmic preparations of immunosuppressants

20. February 2023

Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants are drugs that can inhibit the body’s immune response. Considering...

Influence of PLGA End Groups on the Release Profile of Dexamethasone from Ocular Implants

7. February 2023

The present study deals with the development of dexamethasone (DM)-loaded implants using ester end-capped Resomer RG 502 poly(lactic acid-co-glycolic acid)...

Use of polyvinyl alcohol (PVA) to overcome challenges in ophthalmic formulations

1. February 2023

Successful ophthalmic drug formulations rely on the selection of the correct polymer to ensure the desired characteristics such as retention...

Towards the development of a biorelevant in vitro method for the prediction of nanoemulsion stability on the ocular surface

28. January 2023

Ophthalmic oil-in-water nanoemulsions (NEs) are a complex technological platform, representing an advancement in the treatment of dry eye disease. In...

3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma

24. January 2023

Abstract Objectives To develop a sustained release 5-fluorouracil (5-FU) implant by three-dimensional (3D) printing to effectively prevent conjunctival fibrosis after...

Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

24. January 2023

Diseases affecting the anterior segment of the eye are the primary causes of vision impairment and blindness globally. Drug administration...

Fabrication and Characterisation of 3D-Printed Triamcinolone Acetonide-Loaded Polycaprolactone-Based Ocular Implants

14. January 2023

Triamcinolone acetonide (TA) is a corticosteroid that has been used to treat posterior segment eye diseases. TA is injected intravitreally...

Design and optimization of ciprofloxacin hydrochloride biodegradable 3D printed ocular inserts: Full factorial design and in-vitro and ex-vivo evaluations: Part II

8. January 2023

Coupling hot-melt extrusion (HME) with fused deposition modeling three-dimensional printing (FDM-3DP) can facilitate the fabrication of tailored, patient-centered, and complex-shaped...

Inkjet drug printing onto contact lenses: Deposition optimisation and non-destructive dose verification

3. January 2023

Inkjet printing has the potential to advance the treatment of eye diseases by printing drugs on demand onto contact lenses...

Ocular Delivery