The Use of Polymer Blends in the Treatment of Ocular Diseases

19. July 2022

The eye is an organ with limited drug access due to its anatomical and physiological barriers, and the usual forms...

Non-invasive drug delivery systems mediated by nanocarriers and molecular dynamics simulation for posterior eye disease therapeutics: Virtual screening, construction and comparison

14. July 2022

Local deliver medication in a non-invasive pattern and attaining a long-term sustained release at ocular regions to minimize side effects...

Development and optimization of solid lipid nanoparticles coated with chitosan and poly(2-ethyl-2-oxazoline) for ocular drug delivery of ciprofloxacin

24. June 2022

Many formulation strategies have been employed to improve ocular bioavailability of topical eye drops. The aim of this study was...

Chitosan/sulfobutylether-β-cyclodextrin based nanoparticles coated with thiolated hyaluronic acid for indomethacin ophthalmic delivery

17. June 2022

Indomethacin (IND) is topically administered for the treatment of the anterior segment diseases such as conjunctivitis, uveitis, and inflammation prevention for post-cataract...

Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs

30. May 2022

Poor aqueous solubility of new chemical entities presents various challenges in the development of effective drug delivery systems for various...

Dual Drug Loaded Lipid Nanocarrier Formulations for Topical Ocular Applications

24. May 2022

Introduction: Untreated ocular infections can damage the unique fine structures of the eye with possible visual impairments and blindness. Ciprofloxacin...

Development of α-Tocopherol Succinate-Based Nanostructured Lipid Carriers for Delivery of Paclitaxel

20. May 2022

The management of retinoblastoma (RB) involves the use of invasive treatment regimens. Paclitaxel (PTX), an effective antineoplastic compound used in...

Statistical optimization of voriconazole nanoparticles loaded carboxymethyl chitosan-poloxamer based in situ gel for ocular delivery: In vitro, ex vivo, and toxicity assessment

13. May 2022

The research study reflects the development of novel voriconazole (VCZ) loaded nanoparticles (NPs) for prolonged delivery for the management of...

A Mucin-Deficient Ocular Surface Mimetic Platform for Interrogating Drug Effects on Biolubrication, Antiadhesion Properties, and Barrier Functionality

8. May 2022

Dry eye disease (DED) affects more than 100 million people worldwide, causing significant patient discomfort and imposing a multi-billion-dollar burden...

Formulation design and optimization of cationic-charged liposomes of brimonidine tartrate for effective ocular drug delivery by Design of Experiment (DoE) approach

4. May 2022

Objective The present study was aimed to design and optimize brimonidine tartrate (BRT) loaded cationic-charged liposome formulation with enhanced trans-corneal...

Ocular Delivery