Cellulose and its derivatives for application in 3D printing of pharmaceuticals

9. September 2020

Background Three-dimensional printing (3DP) has emerged as an advanced manufacturing technology capable of producing complex yet precise medicines intended for...

Fused deposition modeling of API-loaded mesoporous magnesium carbonate

3. September 2020

In this thesis, the incorporation of drug loaded mesoporous magnesium carbonate as an excipient for the additive manufacturing of oral...

TSMG processing window based on visual observation

Effect of Hydroxypropyl Cellulose Level on Twin-Screw Melt Granulation of Acetaminophen

31. August 2020

This study investigated the effect of binder level on the physicochemical changes and tabletability of acetaminophen (APAP)-hydroxypropyl cellulose (HPC) granulated...

Polymer Selection for Hot-Melt Extrusion Coupled to Fused Deposition Modelling in Pharmaceutics

27. August 2020

Three-dimensional (3D) printing offers the greatest potential to revolutionize the future of pharmaceutical manufacturing by overcoming challenges of conventional pharmaceutical...

Studying effect of glyceryl palmitostearate amount, manufacturing method and stability on polymorphic transformation and dissolution of rifaximin tablets

24. August 2020

Rifaximin (RFX) exhibit polymorphism and commercial formulation contains the α form. The polymorphic transformation of the RFX in the drug...

Effect of the molecular mobility of water adsorbed by disintegrants on storage-induced hydrolytic degradation of acetylsalicylic acid incorporated into tablets under humid conditions

7. August 2020

The purpose of this study was to investigate the effect of molecular mobility of water adsorbed by disintegrants on the...

Comparison of the batch and continuous high-shear granulators

Tablet Quality-Prediction Model Using Quality Material Attributes: Toward Flexible Switching Between Batch and Continuous Granulation

27. July 2020

Purpose The purpose of the study was to develop a model to predict the critical quality attribute (CQA) of tablets...

Development of a dental pocket drug delivery system based on temperature responsive polymer by the hot melt extrusion method.

23. July 2020

Controlled delivery systems are used to improve therapeutic efficacy and safety of drugs by delivering them at a rate dictated...

In-Depth Study into Polymeric Materials in Low-Density Gastroretentive Formulations

14. July 2020

The extensive use of oral dosage forms for the treatment of diseases may be linked to deficient pharmacokinetic properties. In...

Temperature: an overlooked factor in tablet disintegration

3. June 2020

Disintegration is the first event in the bioavailability cascade after the ingestion of immediate release tablets. Although the influence of...

HPC - hydroxypropyl cellulose