3D printing of solid oral dosage forms: numerous challenges with unique opportunities

25. October 2020

Since the FDA approval of Spritam, there has been a growing interest in the application of 3D printing in pharmaceutical...

Characterizing and Exploring the Differences in Dissolution and Stability Between Crystalline Solid Dispersion and Amorphous Solid Dispersion

30. September 2020

Solid dispersion is one of the most effective ways to improve the dissolution of insoluble drugs. When the carrier can...

Development of Immediate Release (IR) 3D-printed oral dosage forms with focus on industrial relevance

20. September 2020

Pharmaceutical 3D-printing represents a potentially new dosing and manufacturing approach for the pharmaceutical industry, with unique opportunities for personalization of...

Mechanical Characteristics of Orally Disintegrating Films: Comparison of Folding Endurance and Tensile Properties

15. September 2020

The tensile test is the most widely used method for testing the mechanical characteristics of orally disintegrating films (ODFs). The...

Cellulose and its derivatives for application in 3D printing of pharmaceuticals

9. September 2020

Background Three-dimensional printing (3DP) has emerged as an advanced manufacturing technology capable of producing complex yet precise medicines intended for...

Fused deposition modeling of API-loaded mesoporous magnesium carbonate

3. September 2020

In this thesis, the incorporation of drug loaded mesoporous magnesium carbonate as an excipient for the additive manufacturing of oral...

TSMG processing window based on visual observation

Effect of Hydroxypropyl Cellulose Level on Twin-Screw Melt Granulation of Acetaminophen

31. August 2020

This study investigated the effect of binder level on the physicochemical changes and tabletability of acetaminophen (APAP)-hydroxypropyl cellulose (HPC) granulated...

Polymer Selection for Hot-Melt Extrusion Coupled to Fused Deposition Modelling in Pharmaceutics

27. August 2020

Three-dimensional (3D) printing offers the greatest potential to revolutionize the future of pharmaceutical manufacturing by overcoming challenges of conventional pharmaceutical...

Studying effect of glyceryl palmitostearate amount, manufacturing method and stability on polymorphic transformation and dissolution of rifaximin tablets

24. August 2020

Rifaximin (RFX) exhibit polymorphism and commercial formulation contains the α form. The polymorphic transformation of the RFX in the drug...

Effect of the molecular mobility of water adsorbed by disintegrants on storage-induced hydrolytic degradation of acetylsalicylic acid incorporated into tablets under humid conditions

7. August 2020

The purpose of this study was to investigate the effect of molecular mobility of water adsorbed by disintegrants on the...

HPC - hydroxypropyl cellulose