Eudragit® L100/chitosan composite thin bilayer films for intravaginal pH-responsive release of Tenofovir

9. February 2022

The high rate of HIV new infections and AIDS-related deaths each year make prevention tools still necessary today. Different dosage...

graphical abstract of 3D printing of pharmaceutical oral solid dosage forms by fused deposition: the enhancement of printability using plasticised HPMCAS

3D printing of pharmaceutical oral solid dosage forms by fused deposition: the enhancement of printability using plasticised HPMCAS

9. February 2022

3D printing (3DP) by fused deposition modelling (FDM) is one of the most extensively developed methods in additive manufacturing. Optimizing...

Dose-independent Drug Release from 3D Printed Oral Medicines for Patient-specific Dosing to Improve Therapy Safety

8. February 2022

Fused deposition modelling (FDM) 3D printing provides the ability to address individual patients’ therapeutic needs without having to change the...

Fragment of the crystal structure of CTD-CAF, illustrating the channels formed by CTD molecules along the a-axis, in which pairs of CAF molecules are embedded.

Tailoring Chlorthalidone Aqueous Solubility by Cocrystallization: Stability and Dissolution Behavior of a Novel Chlorthalidone-Caffeine Cocrystal

8. February 2022

A cocrystal of the antihypertensive drug chlorthalidone (CTD) with caffeine (CAF) was obtained (CTD-CAF) by the slurry method, for which...

graphical abstract of Revealing the roles of polymers in supersaturation stabilization from the perspective of crystallization behaviors: A case of nimodipine

Revealing the roles of polymers in supersaturation stabilization from the perspective of crystallization behaviors: A case of nimodipine

8. February 2022

Formulating drugs into amorphous solid dispersions (ASDs) represents an attractive means to enhance the aqueous solubility of drugs. Furthermore, water-soluble...

graphical abstract of Moisture sorption by polymeric excipients commonly used in amorphous solid dispersion and its effect on glass transition temperature: I. Polyvinylpyrrolidone and related copolymers

Moisture sorption by polymeric excipients commonly used in amorphous solid dispersion and its effect on glass transition temperature: I. Polyvinylpyrrolidone and related copolymers

7. February 2022

Moisture plays a critical role in the stability of amorphous solid dispersions (ASD) as it can lower the glass transition...

FDM 3D-Printed Sustained-Release Gastric-Floating Verapamil Hydrochloride Formulations with Cylinder, Capsule and Hemisphere Shapes, and Low Infill Percentage

7. February 2022

The aim of this work was to design and fabricate fused deposition modeling (FDM) 3D-printed sustained-release gastric-floating formulations with different...

Polymers