Extreme Extensibility in Physically Cross-Linked Nanocomposite Hydrogels Leveraging Dynamic Polymer–Nanoparticle Interactions

24. August 2022

Abstract Designing yield stress fluids to exhibit desired functional properties is an integral challenge in many applications such as 3D...

Hydroxypropyl cellulose/Polyvinylpyrrolidone Matrix Tablets Containing Ibuprofen: Infiltration, Erosion and Drug Release Characteristics

20. August 2022

The current study aims to prepare the matrix tablet including polyvinylpyrrolidone (PVP), hydroxypropyl cellulose (HPC) and poorly water-soluble ibuprofen (IBU)...

Eudragit® L100/Polyvinyl Alcohol Nanoparticles Impregnated Mucoadhesive Films as Ocular Inserts for Controlled Delivery of Erythromycin: Development, Characterization and In Vivo Evaluation

16. August 2022

The fast elimination of drugs from the cornea is one of many challenges associated with the topical administration of conventional...

Moisture Sorption by Polymeric Excipients Commonly Used in Amorphous Solid Dispersions and its Effect on Glass Transition Temperature: II. Cellulosic Polymers

16. August 2022

Moisture sorption by polymeric carriers used for the development of amorphous solid dispersions (ASDs) plays a critical role in the...

Comparative Study of Methods for the Pharmaceutical Preparation and Effectiveness of Darunavir Ethanolate Compositions with Mesoporous Carriers and Polymer Solid Dispersions

13. August 2022

Purpose The aim of this work was to study the effectiveness of various methods for improving the solubility and bioavailability...

Bile and excipient interactions directing drug pharmacokinetics in rats

10. August 2022

Bile solubilization plays a major role in the absorption of poorly water-soluble drugs. Excipients used in oral drug formulations impact...

Immediate release 3D printed oral dosage forms: How different polymers have been explored to reach suitable drug release behaviour

10. August 2022

Three-dimensional (3D) printing has been gaining attention as a new technological approach to obtain immediate release (IR) dosage forms. The...

Targeted colonic release formulations of mesalazine – A clinical pharmaco-scintigraphic proof-of-concept study in healthy subjects and patients with mildly active ulcerative colitis

8. August 2022

Colonic targeting of orally applied therapeutic drugs remains a challenge. Tablet coatings relying on gastrointestinal pH and colonic bacterial enzymes as triggers...

Silicon Oxycarbide Porous Particles and Film Coating as Strategies for Tenofovir Controlled Release in Vaginal Tablets for HIV Prevention

5. August 2022

Sustained release of antiretroviral drugs is currently the most encouraging strategy for the prevention of the sexual transmission of HIV....

Formulation and Evaluation of Eudragit® RL Polymeric Double Layer Films for Prolonged-Release Transdermal Delivery of Tamsulosin Hydrochloride

4. August 2022

Transdermal drug delivery systems (TDDSs) were developed for prolonged tamsulosin (TMS) delivery. Double layer (DL) TDDSs were prepared using Eudragit®...

Polymers