Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems – Part 1

Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems

See the new book, edited by Kuldeep Vinchurkar, Sheetal Mane, Dinesh Kumar Mishra. This book provides a roadmap for creating customized, precision drug delivery systems and advancing personalized medicine by introducing the revolutionary, transformative role of 3D printing technology in medicine.

Description: The convergence of advanced manufacturing techniques with the complexities of pharmaceutical formulation has opened new frontiers of innovation, enabling unprecedented precision in drug delivery, tailored therapies, and complex dosage designs. From the creation of personalized drug formulations designed to meet the specific needs of individual patients to the development of complex, multi-functional drug delivery systems, the chapters within this volume explore a wide array of applications. This book is a groundbreaking resource that delves into the transformative role of 3D printing technology in the pharmaceutical field. Offering insights into customized and precision drug delivery systems, it highlights the synergy between advanced manufacturing techniques and pharmaceutical sciences. The book provides a balanced blend of theory and practical applications, presenting a roadmap for researchers and professionals to integrate 3D printing into their pharmaceutical processes. It discusses the role of innovative materials, cutting-edge technologies, and regulatory perspectives while highlighting the challenges and future trends in the field. By offering contributions from distinguished experts, the book serves as a comprehensive reference for understanding the potential of 3D printing to revolutionize drug delivery and advance personalized medicine.

Readers will find this volume:

• Explores cutting-edge 3D printing applications in pharmaceutical sciences, emphasizing precision and innovation;
• Covers practical and theoretical insights into customized drug delivery systems using 3D printing;
• Includes detailed case studies and emerging trends for academic and industrial professionals;
• Features contributions from leading experts and researchers in the field.

Chapter 4

3D Printing of Solid Dosage Forms

Three-dimensional (3D) printing is transforming the pharmaceutical landscape, particularly in the design of solid dosage forms (SODFs) as advanced drug delivery. This technology offers significant advantages over traditional manufacturing methods, allowing for the development of patient-specific dosage forms with complex geometries and controlled drug release characteristics. The FDA’s approval of Spritam ^® , the first 3D-printed tablet, marked a significant milestone and increased research and development in this area. Traditional platforms lack the flexibility needed for personalized medicine, but 3D printing can rapidly prototype various dosage forms without expensive equipment. This adaptability is very important for tailoring individualized drug doses and release profiles to meet specific patient needs. 3D printing technology offers a promising approach to creating solid dosage forms in nanomedicine that feature improved functionality and tailored characteristics for individual patients. Current research in this area has significant potential to transform drug delivery systems and enhance treatment outcomes across various medical conditions. As scientists delve deeper into the applications of 3D printing in pharmaceuticals, the prospects for personalized medicine and precise drug delivery are becoming more attainable.

See the chapter

3D Printing of Solid Dosage Forms, Ashwin Kuchekar, Prajakta Wagh, Harshavardhan Karnik, Ashwini Gawade, Book Editor(s):Kuldeep Vinchurkar, Sheetal Mane, Dinesh Kumar Mishra, First published: 07 November 2025 https://doi.org/10.1002/9781394337576.ch4

Chapter 7

3D Printing in Drug Delivery System

Drug delivery methods are undergoing a revolution thanks to three-dimensional (3D) printing, which makes it possible to produce sophisticated, individually tailored pharmaceuticals.

The emergence of 3D printing in the 1980s has transformed several domains of research, including the pharmaceutical sector. The primary objective is to provide customized, sophisticated goods on demand using an affordable production approach. Several research organizations have been interested in 3D printing during the past few decades to produce various medication delivery systems. There have been many more publications since the first 3D-printed pharmaceutical product was approved in 2015. This technology allows for the development of custom dosage forms, including tablets, capsules, implants, and transdermal systems, with precise control over drug release profiles and dosages. Several 3D printing techniques, such as FDM, SLS, as well as inkjet printing, are employed to manufacture these drug delivery devices. The benefits of 3D printing in this context are enhanced flexibility, cost-effectiveness, and the capability to produce intricate designs that are impractical with conventional manufacturing methods. Ongoing research and development are expected to expand the applications of 3D printing in personalized medicine and multi-drug delivery systems, further advancing the capabilities of this innovative technology. Drug delivery systems are divided into subgroups that include micro- and nanoscale dosage forms, tablets, capsules, orodispersible films, implants, transdermal delivery systems, microneedles, and vaginal drug delivery systems.

The field is poised for further growth with ongoing research into new materials and printing techniques. Future developments may include more sophisticated multi-drug delivery systems and broader applications in personalized medicine.

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3D Printing in Drug Delivery System, Satish Polshettiwar, Shrikant Dargude, Pranali Polshettiwar, Saloni Ghodmare, Swati Jagdale, Kuldeep Vinchurkar, Book Editor(s):Kuldeep Vinchurkar, Sheetal Mane, Dinesh Kumar Mishra, First published: 07 November 2025, https://doi.org/10.1002/9781394337576.ch7

Chapter 8

3D Bioprinting in Pharmaceutical Research

3D bioprinting techniques have significantly influenced pharmaceutical research, offering unmatched flexibility in the design and production of intricate drug delivery systems. This technology facilitates the creation of personalized medications, including polypills that amalgamate multiple drugs into a single dosage form. Bioprinting facilitates the creation of three-dimensional tissue models that more precisely emulate in vivo conditions compared to conventional two-dimensional models, potentially reducing the need for animal experimentation. Various bioprinting methodologies, such as extrusion-based, inkjet-based, pressure-assisted, and laser-assisted biological printing, have been utilized to create functional tissues, scaffolds, and customized drug delivery systems. The integration of CAD (computer-aided design) facilitates accurate control of the release of drugs, dosage, and combinations, leading to improved patient adherence and therapeutic outcomes. Although still in its nascent phase in the pharmaceutical industry, 3D bioprinting is poised to revolutionize the development of medicines and personalized healthcare.

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3D Bioprinting in Pharmaceutical Research, Vijaya Padwal, Sachin Kothawade, Sandesh Bole, Kuldeep Vinchurkar, Book Editor(s):Kuldeep Vinchurkar, Sheetal Mane, Dinesh Kumar Mishra, First published: 07 November 2025 https://doi.org/10.1002/9781394337576.ch8

See the full book here

Kuldeep Vinchurkar, Sheetal Mane, Dinesh Kumar Mishra, Precision 3D Printing in Pharmaceutical Sciences: A Transformative Shift in Drug Manufacturing and Delivery Systems, First published:7 November 2025, Print ISBN:9781394337545 |Online ISBN:9781394337576 |DOI:10.1002/9781394337576, © 2025 Scrivener Publishing LLC