Solubility Enhancement

Abstract Purpose This study aims to evaluate the ability of various cyclodextrins (CDs) to enhance the aqueous solubility of haloperidol...

Abstract Introduction: The cold-burst method presents a novel, energy-efficient, and cost-effective approach for solid lipid nanoparticle (SLN) production compared to...

Press Release January 23, 2025 COPENHAGEN, Denmark: Zerion Pharma A/S (“ZERION”) today announces a partnership with Aché Laboratorios Farmacêuticos S.A....

Abstract This study investigates the solubility and miscibility of ibuprofen (IBU) with four pharmaceutical polymers, KOLVA64®, KOL17PF®, HPMCAS, and Eudragit®...

Oral drug delivery to the colon remains a formidable challenge due to the harsh conditions of the upper gastrointestinal tract,...

Abstract This study introduced a novel vectorized Biopharmaceutics Classification System (BCS) model designed to evaluate the biopharmaceutical properties of active...

Abstract Polyethoxylated (PEO)-based nonionic surfactants, such as D-α-Tocopheryl polyethylene glycol succinate (TPGS), offer significant advantages in drug delivery due to...

Abstract Amorphous solid dispersions (ASDs) make a significant contribution to enhancing the solubility of poorly soluble drugs. The incorporation of...

Abstract Lornoxicam (LOX) is (NSAID); it is a crystalline powder that ranges in color from orange to yellow and is...

Abstract Aceclofenac (ACF), a Non-Steroidal Anti-Inflammatory Drug (NSAID), is formulated with Soluplus® (SOLP) to enhance solubility and bioavailability. This study...