Stabilizer

The ‘repurposed drug,’ disulfiram (DSF), is an inexpensive FDA-approved anti-alcoholism drug with multi-target anti-cancer effect. However, the use of DSF...

Trehalose is a non-reducing disaccharide consisting of two glucose molecules linked by an α, α–1,1 bond. Pfanstiehl Brand, High Purity...

11. July 2018 New surfactant replacement offers a promising alternative to polysorbates for stabilizing proteins   CAMBRIDGE, Mass. – July 11,...

The U.S. Pharmacopeia defines excipients as substances other than the active pharmaceutic ingredient (API) that are added in a drug...

23. January 2018 Abstract Glucagon is a peptide hormone used for the treatment of hypoglycemia; however, its clinical potential is...

24. September 2017 Abstract The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus®polymers...

09. August 2017 Objectives This study reports global and local monoclonal antibody (mAb)–excipient interactions and the resulting thermodynamic and stabilization...

19. April 2017 Abstract We developed a step-by-step experimental protocol using differential scanning calorimetry (DSC), dynamic vapour sorption (DVS), polarized...

16. April 2017   Purpose Understanding the mechanism of protein-excipient interaction and illuminating the influencing factors on protein stability are...

03. January 2017 Abstract Aspirin is apt to hydrolyze. In order to improve its stability, a new method has been...