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MEDELPHARM
Shaping tomorrows tablets at Compaction Simulation Forum 2025 in San Francisco
From June 9 to 11, 2025, MEDELPHARM and KORSCH took part in the Compaction Simulation Forum (CSF) in San Francisco. Known for their leadership in compaction simulation, both companies used this year’s event to share innovative research through scientific posters, focusing on real…
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R&D and Process Support – by MEDELPHARM
Leverage our Expertise and Advanced Technologies to Streamline Product Development and Process Optimization
KORSCH & MEDELPHARM :
Your Trusted Partner for Tableting Solutions!
Understand & Develop
Material Characterizations
Formulation Development Support
Transfer &…
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STYL’One Nano – The Benchtop Compaction Simulator
Research and Development in Focus
With over 125 years of combined experience with small-scale, fully instrumented machines, KORSCH and MEDELPHARM offer the most advanced line of tablet compression technology in the world.
The combined R&D product line meets and exceeds every requirement,…
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Influence of material and process parameters on the correction factor Kp in roller compaction…
Abstract
It is widely believed that compaction simulators can replicate the uniaxial compression process of a roller compactor. The correction factor (Kp) is a parameter used to adjust a mathematical model for compaction simulation to obtain the same product relative density, therefore accounting…
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STYL’One Evo – Advanced Compaction Simulator
Research and Development in Focus
With over 125 years of combined experience with small-scale, fully instrumented machines, KORSCH and MEDELPHARM offer the most advanced line of tablet compression technology in the world.
The combined R&D product line meets and exceeds every requirement,…
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Does tablet shape and height influence survival of fluidized bed-granulated living microorganisms…
Abstract
The provision of effective probiotic formulations requires gentle processing to maintain the viability of the probiotic microorganisms, which is essential for their health-promoting effects. The drying of microorganisms by fluidized bed spray granulation and subsequent processing of the…
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Effect of Magnesium Stearate Lubrication on the Tableting of Spray-dried Grades of Mannitol and…
This poster was presented at the ECP 2025 in Porto
Introduction
Polyols, such as mannitol, sorbitol, and isomalt, are widely used as excipients for tablet direct compression formulations because of their excellent compaction properties, flowability, as well as high and pH independent…
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Design of Experiments (DOE) – An essential tool to better understand tablet formulations
This paper covers a brief overview of the steps for pharmaceutical product development under the quality by design (QbD) framework; introduces design of experiments (DoE) applied to formulation of tablets and gives an example of how to design piroxicam amorphous solid dispersions (ASD) tablets using…
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Evolution of critical tablet attributes with temperature – ECP 2025 Poster
This poster was presented at the ECP 2025 in Porto
Goal
Determine the impact of the temperature on tablet attributes: appearance and hardness.
Materials and Methods
MATERIAL 2 batches of customer formulation with Poloxane and PEG6000
PRESS MODEL STYL‘One Evo (MEDELPHARM, Beynost,…
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Compaction Characterisation of Piroxicam Amorphous Solid Dispersions Formulations
See another MEDELPHARM bulletin:
Amorphous solid dispersions (ASDs) have been widely used to improve the bioavailability of poorly water-soluble drugs . They are comprised of high molar mass polymer carriers that stabilise the active pharmaceutical ingredients (APIs) in their amorphous state.…
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