STYL’One Nano – The Benchtop Compaction Simulator
Research and Development in Focus
With over 125 years of combined experience with small-scale, fully instrumented machines, KORSCH and MEDELPHARM offer the most advanced line of tablet compression technology in the world.
The combined R&D product line meets and exceeds every requirement, from early-stage powder characterization and formulation development, to scale-up and production support.
It covers the full spectrum of tableting technology from single-layer to five-layer, as well as Tab-in-Tab. MEDELPHARM compaction simulators are the perfect complement to the KORSCH product line.
Flexibility of Use
The STYL’One Nano is a compact tabletop R&D tablet press that can be installed on an existing bench, on an optional mobile cart or even inside a downflow booth. The machine is easy to clean due to a GMP working area featuring smooth surfaces and full accessibility.
Material Understanding
API / Excipient characterization
- Work with minimal material quantities
- Assess criticality of material attributes
- Compare different material suppliers
Analytical development
- Easy and consistent sample production for analytical method development and validation
Product Development
Tablet formulation development
- Test and optimize formulations
- Evaluate the effect of Process Parameters (PP)
- Select the most suitable manufacturing process
Production of small batches
- Feasibility assessment and prototyping
- Early stability batches
Different Filling Solutions
- Manual Die Filling
- Gravity Feeder
- Forced Feeder
Flexible Tooling
The machine permits the use of standard EU/TSM B, BB, BBS and D tooling of any shapes, including multi-tip and oversized tooling. The STYL’One Nano permits a wide range of tablet formats, including mini-tablets of 2 mm to a maximum tablet diameter of 40 mm.
- Simple tool setup and exchange
- Minimal parts to assemble
- Change over in 5 minutes
- Up to 40 mm diameter oversized tooling
Advanced Instrumentation
The STYL’One Nano is designed with the most advanced instrumentation to measure the upper and lower compression force and punch position. Mechanical deformation is automatically measured and compensated for by the software.
Standard Instrumentation
- Precompression force
- Main compression force
- Ejection force
- Upper punch displacement
- Lower punch displacement
See the full technical brochure on STYL’One Nano here
(click the picture to download the brochure)
Source: MEDELPHARM technical brochure STYL’One Nano
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