Roquette

Abstract Bio-adhesive buccal-delivery of drugs is one of alternative to the oral route of drug administration, particularly drugs that are...

Abstract Minitablets represent a promising oral solid dosage form that allows for a wide range of doses within a single...

Abstract Ellagitannins (ETs) from Punica granatum leaves are susceptible to degradation under less acidic pH conditions, which may compromise their use as...

Abstract Although localized strain critically affects the mechanical integrity of pharmaceutical tablets, conventional macroscopic tests cannot capture spatial strain distributions....

Abstract Objectives: Fixed-dose combination tablets containing sitagliptin hydrochloride (SG) and metformin hydrochloride (MF) are a mainstay in the clinical management...

Abstract Aim Efonidipine hydrochloride ethanolate (EHE), a BCS Class II calcium channel blocker, exhibits extremely poor aqueous solubility and undergoes...

This year CPHI Europe opens its doors in Milan at Fiera Milano. From 6th to 8th October you can have a...

Abstract The generation of N-nitrosamine compounds (NOCs) in drugs presents a critical regulatory challenge owing to their potential mutagenicity and exceptionally...

Abstract The stability of moisture-sensitive active pharmaceutical ingredients (APIs) in solid dosage forms is a key determinant of product quality...

Abstract Lamination is a common defect observed during pharmaceutical tablet compression and can be attributed to air entrapment (lamination type...