Free-flow for direct compression and enhanced adsorption capacity?
BIOGRUND’s one-step tabletting agent CompactCel® SIL provides an easy to use, granulated and homogeneous compound of Silica and PVP/NaCMC or HPC/NaCMC, which acts as a perfect dry binder granulate. With CompactCel® SIL it is possible to produce direct compressed tablets containing excipients and a high content of active ingredients (which are normally incompressible) in one step.
A wet granulation step to isolate the active ingredients with an excipient is in most cases not needed. Further- more liquid ingredients can be converted into powders. The use of Silica within the compound improves free flowing properties, gives better compaction and a superior adsorptive capacity for increased stability (by adsorbing surrounding liquids or moisture) and an improved dissolution profile. Download product information here: compactcel_sil_biogrund_1561467423.pdf