Continuous manufacturing

While measurement and monitoring of powder/particulate mass flow rate are not essential to the execution of traditional batch pharmaceutical tablet...

The effect of two screw configurations with varying stagger angle was evaluated on the liquid amount required to produce good...

The material properties of excipients and active pharmaceutical ingredients (API's) are important parameters that affect blend uniformity of pharmaceutical powder formulations. With...

The influence of different tableting process parameters on lead-lag was studied by collecting in-line near-infrared (NIR) spectra in the filling...

While continuous manufacturing (CM) of pharmaceutical solid-based drug products has been shown to be advantageous for improving the product quality...

Voriconazole (VRC), a second generation triazole derivative emerged as a promising candidate for the treatment of fungal infections. Voriconazole is commercially available as oral...

In this paper we present a thorough description of the digital twin development for a continuous pharmaceutical powder blending process...

Toward further implementation of continuous tablet manufacturing, one key issue is the time needed for start-up operation because it could...

Purpose In the pharmaceutical industry, there has been a growing interest in continuous manufacturing in recent years. Many efforts have...

Highlights • Model based approach to quantify fluidization quality, exclusively using the temperature profile. • Approach is suited for drying...