Study on Applicability of ODTs with Co-processed Excipient to Continuous Manufacturing Process

31. March 2021

“Continuous Manufacturing (CM)” is a manufacturing method in which raw or blended materials are continuously charged to the processing line,...

Characterization of a Novel Drying Technology for Continuous Processing of Cohesive Materials: An Ibuprofen Case Study

15. March 2021

This work addresses the influence of several process parameters on the performance of a novel drying device (patent NL2020740B1). In...

Continuous Mixing Technology: Characterization of a vertical mixer using residence time distribution

22. February 2021

Continuous powder mixing technology (CMT) application during continuous direct compression has emerged as a leading technology used in the development...

Impact of excipients on batch and continuous powder blending

16. February 2021

Stimulated by Pharma 4.0, the pharmaceutical industry is changing from batch-wise to continuous manufacturing. Therefore, individual processing steps such as...

Loss-in-weight feeding, powder flow and electrostatic evaluation for direct compression hydroxypropyl methylcellulose (HPMC) to support continuous manufacturing

10. February 2021

Minimizing variability in the feeding process is important for continuous manufacturing since materials are fed individually and can impact the...

Concise overview of the critical binder attributes influencing the binder effectiveness for a poorly and highly soluble formulation

Identifying Critical Binder Attributes to Facilitate Binder Selection for Efficient Formulation Development in a Continuous Twin Screw Wet Granulation Process

9. February 2021

The suitability of pharmaceutical binders for continuous twin-screw wet granulation was investigated as the pharmaceutical industry is undergoing a switch...

Material tracking in a continuous direct capsule-filling

$Roll Compactor with In-line laser diffraction to measure granule size$

Implementing Feedback Granule Size Control in a Continuous Dry Granulation Line Using Controlled Impeller Speed of the Granulation Unit, Compaction Force and Gap Width

22. December 2020

In continuous manufacturing of pharmaceuticals, dry granulation is of interest because of its large throughput capacity and energy efficiency. In...

Continuous manufacturing