Hot-melt extrusion

Coupling hot-melt extrusion (HME) with fused deposition modeling three-dimensional printing (FDM-3DP) can facilitate the fabrication of tailored, patient-centered, and complex-shaped...

This work developed high drug-load pellets for colon targeting in minimal steps by coupling hot-melt extrusion (HME) with a die-surface...

Pharmaceutical amorphous solid dispersions (ASDs) represent a widely used technology to increase the bioavailability of active pharmaceutical ingredients (APIs). ASDs...

Reports in the literature indicate that hot-melt extrusion (HME) processing techniques could alter the mechanical properties of the pharmaceutical physical...

The formulation development of amorphous solid dispersions (ASDs) towards a patient-friendly oral solid dosage form is proving to be still...

Characterization of drug release from modified-release products in the presence of alcohol is required to evaluate the possibility of dose...

Pharmaceutical product development guided by Quality by Design (QbD) is based on a complete understanding of the critical process parameters...

Two Polyvinyl Alcohol Grades Providing Excellent Performance for Solubility Enhancement and Stabilization Poor solubility of APIs is a critical challenge...

Florham Park, New Jersey, December 5, 2022 – BASF Pharma Solutions, a global business unit of BASF, announces today that...

The aim of this study was to develop a continuous pilot-scale solidification and characterization of self-emulsifying drug delivery systems (SEDDSs)...