Hot-melt extrusion

New molecular entities (NMEs) are becoming larger and more lipophilic and, as a result, less soluble. While approximately 40% of...

Solid dispersion (SD) is one of the oldest and widely utilized techniques to improve the solubility of slowly dissolving drugs....

Hot-melt extrusion has found extensive application as a feasible pharmaceutical technological option over recent years. HME applications include solubility enhancement,...

The current study evaluated the effect of location and amount of various superdisintegrants on the properties of tablets made by...

The oral route is the most common form of drug administration, being a safe and convenient, particularly for solid oral...

Following our study on the impact of hot melt extrusion (HME) process conditions on the product quality, we expanded our...

In this series of webinars we will discuss the latest developments in the fields of amorphous solid dispersion (ASD) focusing...

Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and bioavailability of poorly water-soluble drugs. Various approaches have been...

To improve patient compliance and personalised drug delivery, long-acting drug delivery devices (LADDDs), such as implants and inserts, greatly benefit...

Introduction: Amorphous formulation technologies to improve oral absorption of poorly soluble active pharmaceutical ingredients (APIs) have become increasingly prevalent. Currently,...