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      • Mineral Stearates
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Startseite » News » Structural and functional analysis of a new co-processed tableting excipient for food compaction processes

Structural and functional analysis of a new co-processed tableting excipient for food compaction processes

2. July 2023
Structural and functional analysis of a new co-processed tableting excipient for food compaction processes

Structural and functional analysis of a new co-processed tableting excipient for food compaction processes

Food compacts are convenient to industry and customers and must primarily possess a sufficient strength to withstand packaging processing and customer handling. In contrast to pharmaceutical applications, the choice of excipients is usually limited to necessary ingredients of the final food product. In accordance, novel, better performing materials derived from advanced processing of common food constituents are highly attractive. This study thoroughly characterizes the properties of such a novel, co-processed food material called “Salt-Starch” to demonstrate its superior tableting behavior and to investigate the cause of its superiority.

For a fundamental understanding of the binding mechanisms and the resulting structure, tabletability, compressibility, compactibility and elastic recovery of compacts based on Salt-Starch, its sole starting components with different particle sizes and their physical blends are investigated. Results indicate, that the specific structure of a viscoelastic continuous phase of starch and a brittle-ductile dispersed phase of (sub-)micron-sized sodium chloride lead to superior strength of Salt-Starch, which cannot be achieved by physical mixtures. Compacts tensile strength is elevated 40 times at an applied pressure of 55 MPa and elastic recovery is less than half compared to the elastic recovery of binary mixture tablets.

Read more here

Materials

Salt-Starch (SaS, Nestlé Nahrungsmittelforschung GmbH, Germany) is a new tableting excipient for food compaction, consisting of sodium chloride and pre-gelatinized pea starch in weight fractions of 3:2. The manufacturing process of SaS is already documented (Bobe et al., 2019b). Sodium chloride (NaCl, Salta Siede Table salt, Südsalz GmbH, Germany) and native pea starch are the starting materials for the SaS production.

René Rösemeier-Scheumann, Lars Wagner, Ulrich Bobe, Annabel Bozon, Arno Kwade, Jan Henrik Finke, Structural and functional analysis of a new co-processed tableting excipient for food compaction processes, Journal of Food Engineering, 2023, 111624, ISSN 0260-8774, https://doi.org/10.1016/j.jfoodeng.2023.111624.


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      • Colour / Color
      • Coating Systems and Additives
      • Controlled Release Excipient
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      • Disintegrant / Superdisintergrant
      • Drug Carrier
    • Emulsifier – Glidant
      • Emulsifier
      • Excipient for Inhalation
      • Filler
      • Film former
      • Flavour / Flavor
      • Glidant
    • Lubricant – Preservative
      • Lubricant
      • Nanotechnology
      • Orally Dissolving Technology Excipient
      • Pellet
      • Plasticizer
      • Preservative
    • Solubilizer – Viscocity Agent
      • Solubilizer
      • Speciality Excipient
      • Surfactants
      • Suspension Agent
      • Sustained Release Agent
      • Sweeteners
      • Taste Masking
      • Topical Excipient
      • Viscosity Agent
  • Sources
    • Handbook of Pharmaceutical Excipients – 9th Edition
    • EINECS Numbers
    • Excipient DMF List
    • Excipient cGMP Certification Organisations
    • FDA Inactive Ingredient List
    • FDA GRAS Substances (SCOGS) Database
    • Excipient E-Numbers
    • Whitepapers / Publications
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  • Suppliers
    • A-B
      • ADM
      • ARMOR PHARMA
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      • Ashland
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      • Budenheim
    • C-G
      • Captisol
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      • Cyclolab
      • DFE Pharma
      • DuPont Pharma Solutions
      • Evonik
      • Fuji Chemical Industries
      • Gattefossé
      • Gangwal Healthcare
    • I-O
      • ingredientpharm
      • IOI Oleochemical
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      • Kerry
      • KLK Oleo Life Science
      • Lactalis Ingredients Pharma
      • Lipoid
      • Dr. Paul Lohmann
      • Lubrizol
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