The R&D department of IOI Oleo GmbH supports you – from the idea to the first product

As a leading company in the field of speciality lipids and pharmaceutical oleochemicals, IOI Oleo GmbH develops innovative and sustainable processes, products and formulations at its research centre in Witten

In addition to its expertise in the field of structural and product development, IOI Oleo GmbH has increasingly expanded its scale-up and process development activities in recent years. Since 2021, Research and Development has been able to scale up from the laboratory to the pilot plant scale, including for clinical studies, by building a cGMP-certified 150 kg pilot plant. The design of the plant allows both liquid and solid products (temp 80 °C) to be processed and variable batch sizes of 50-150 kg to be implemented (read more about our R&D department here).

This offers you the following advantages:

• Guarantee of scalability in product development, thus reducing the risk in your development
• Provision of larger quantities of material for your development and scale-up activities
• Clinical trial supply under cGMP conditions
• Shortened project times
• Contract manufacturing option

The first step towards a new product

Yet another advantage is the cGMP certification of the pilot plant, which enables the production and provision of material for clinical trials under cGMP conditions.

IOI OLEO GMBH – MORE INFORMATION 

Project example:

DYNASAN® CrystalCONTROL L – A new development standard from IOI Oleo GmbH

At the beginning of 2023, our CARE Studio and R&D department launched a new project to produce polymorph-free stick formulations (DYNASAN® CrystalCONTROL L – Formulator’s jewel for worry-free processes). In a constructive and productive project planning process, the idea for DYNASAN® CrystalCONTROL L was successfully implemented within a year.

The close collaboration between development and application went through the following steps:

• Production of the first prototypes up to the kilogram scale
• Evaluation and optimisation of the prototypes in initial application-related tests and preformulations
• Complete characterisation of the target product, including initial analytical method development
• Scale-up to provide samples on a 150 kg scale
• Implementation on variable production scale

DYNASAN® – SHOP

Read more here

Source: IOI Oleo GmbH, website “The R&D department of IOI Oleo GmbH supports you – from the idea to the first product“

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