Hollow microneedles for ocular drug delivery

4. June 2024

Microneedles (MNs) are micron-sized needles, typically <2 mm in length, arranged either as an array or as single needle. These MNs...

Extending the Use of Optical Coherence Tomography to Scattering Coatings Containing Pigments

26. January 2024

Coating thickness is a critical quality attribute of many coated tablets. Functional coatings ensure correct drug release kinetics or protection...

An Integrated Real-time Monitoring and Statistical Process Control Approach for Coating Process and Product Quality via In-line Optical Coherence Tomography

1. December 2023

Abstract Purpose The thickness and other quality aspects of pharmaceutical coatings can be significantly impacted by coating process conditions. Under...

Optical Methods for Non-Invasive Determination of Skin Penetration: Current Trends, Advances, Possibilities, Prospects, and Translation into In Vivo Human Studies

16. September 2023

Information on the penetration depth, pathways, metabolization, storage of vehicles, active pharmaceutical ingredients (APIs), and functional cosmetic ingredients (FCIs) of...

Prediction of dissolution performance of uncoated solid oral dosage forms via optical coherence tomography

18. July 2023

Abstract Real-time prediction of the dissolution behavior of solid oral dosage forms is an important research topic. Although methods such...

Optical Coherence Tomography as a novel tool for non-invasive membrane thickness monitoring of co-extruded drug-delivery systems

8. July 2023

Abstract Co-extruded core-membrane formulations have been extensively explored as long-acting subcutaneous implants or vaginal inserts, guaranteeing zero-order release. Although the...

A validation of discrete-element model simulations for predicting tablet coating variability

16. June 2023

Abstract Achieving an even coating distribution on tablets during the coating process can be challenging, not to mention the challenges...

Optical Coherence Tomography as a novel tool for non-invasive membrane thickness monitoring of co-extruded drug-delivery systems

7. May 2023

Abstract Co-extruded core-membrane formulations have been extensively explored as long-acting subcutaneous implants or vaginal inserts, guaranteeing zero-order release. Although the...

Hydroquinone cream-based polymer microneedle roller for the combined treatment of large-area chloasma

27. February 2023

Melasma is a common hyperpigmented skin condition that occurs on the face and other areas prone to light exposure, seriously...

Microneedles assisted controlled and improved transdermal delivery of high molecular drugs via in situ forming depot thermoresponsive poloxamers gels in skin microchannels

10. August 2022

Skin is considered as an attractive route for variety of drug molecule administration. However, it is proved to be the...

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