Ascertain a minimum coating thickness for acid protection of enteric coatings by means of optical coherence tomograph

2. June 2022

Enteric coatings are designed to protect active pharmaceutical ingredients (APIs) against untimely release in the stomach. Acid protection of such...

graphical abstract of Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness

Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness

12. June 2021

The feasibility of Optical Coherence Tomography (OCT) for in-line monitoring of pharmaceutical film coating processes has recently been demonstrated. OCT...

At-line sampling device with a rotating drum and an in-line OCT sensor

Feasibility of In-line monitoring of critical coating quality attributes via OCT: Thickness, variability, film homogeneity and roughness

22. December 2020

The feasibility of Optical Coherence Tomography (OCT) for in-line monitoring of pharmaceutical film coating processes has recently been demonstrated. OCT...

Non-intrusive high resolution in-vitro measurement of regional drug powder deposition

16. April 2020

Optical Coherence Tomography (OCT) is a high-resolution and non-invasive cross-sectional imaging technique mainly used for medical imaging and industrial non-destructive...

Advanced Tablet Coating Development: Applying Optical Coherence Tomography (OCT) as a PAT Tool for PVA Based Coatings

4. December 2019

Purpose: Novel tablet coating approaches include the development of continuous coating technologies. This requires a high level of automation to...

At-line Validation of Optical Coherence Tomography as In-line/At-line Coating Thickness Measurement Method

14. November 2019

Optical Coherence Tomography (OCT) is a promising technology for monitoring of pharmaceutical coating processes. However, the pharmaceutical development and manufacturing...

Measurement of granule layer thickness in a spouted bed coating process via optical coherence tomography

27. August 2019

In this work a recently developed in-line measurement technique for monitoring of coating thickness was applied to a spray-coating process...

Shedding Light on Coatings

22. May 2019

Real-time Monitoring of Coating Quality at Industrial Scale Optical Coherence Tomography (OCT) is increasingly being used for studies of pharmaceutical...

Optical coherence tomography as a novel tool for in-line monitoring of a pharmaceutical film-coating process

23. October 2018

Optical coherence tomography (OCT) is a contact-free non-destructive high-resolution imaging technique based on low-coherence interferometry. This study investigates the application...

Calibration-free in-line monitoring of pellet coating processes via optical coherence tomography

18. October 2018

The paper presents a new in-line measurement technique for determining the coating thickness and uniformity of pharmaceutical pellets during film-coating...

OCT