Enhanced Anti-Herpetic Activity of Valacyclovir Loaded in Sulfobutyl-ether-β-cyclodextrin-decorated Chitosan Nanodroplets

16. October 2023

Valacyclovir (VACV) was developed as a prodrug of the most common anti-herpetic drug Acyclovir (ACV), aiming to enhance its bioavailability....

Influence of Poloxamer 188 on Anti-Inflammatory and Analgesic Effects of Diclofenac-loaded Nanoemulsion: Formulation, Optimization and In Vitro/In Vivo Evaluation

13. October 2023

Abstract In this study, a polymer-stabilized nanoemulsion (PNE) was developed to improve the inflammatory and analgesic activities of diclofenac (DA)....

Structural modifications for the conversion of proteins and peptides into stable dried powder formulations: A review

10. October 2023

The drying of biomolecules into powdered formulations has become the main form of long-term product stabilisation, allowing for the delivery...

Tioconazole-Loaded Transethosomal Gel Using Box–Behnken Design for Topical Applications: In Vitro, In Vivo, and Molecular Docking Approaches

7. October 2023

Tioconazole (TCZ) is a broad-spectrum fungicidal BCS class II drug with reported activity against Candida albicans, dermatophytes, and certain Staphylococci bacteria. We report the...

Development of Osthole-Loaded Microemulsions as a Prospective Ocular Delivery System for the Treatment of Corneal Neovascularization: In Vitro and In Vivo Assessments

6. October 2023

Osthole (OST), a natural coumarin compound, has shown a significant inhibitory effect on corneal neovascularization (CNV). But, its effect on...

Formulation And Characterization Of Provesicular Based Drug Delivery System For Effective Transdermal Delivery Of Antifungal Drug

5. October 2023

Oral intake of Itraconazole (ITZ) causes severe side effects in the gastrointestinal tract and has low bioavailability ~55%. Owing to...

Design and development of donepezil hydrochloride loaded nanostructured lipid carriers for efficient management of Alzheimer’s disease

5. October 2023

Objective The primary objective of this study was to develop nanostructured lipid carriers of donepezil hydrochloride (DNZ HCl) for effective...

Development and Optimization of a Novel Lozenge Containing a Metronidazole-Peppermint Oil-Tranexamic Acid Self-Nanoemulsified Delivery System to Be Used after Dental Extraction: In Vitro Evaluation and In Vivo Appraisal

3. October 2023

In-depth studies on essential oil–based nanoemulsions (NEs) have centered on a variety of oral health issues. NEs improve the delivery...

Table 2: Instances of substances that have been employed and assessed as new excipients in medicinal products authorized through the centralized procedure in the EU.

A Review On Novel Excipients

29. September 2023

ABSTRACT The field of pharmaceutical formulation is constantly evolving, driven by the need for improved drug delivery systems and enhanced...

Design and development of lipid modified arginine based self-nanoemulsifying drug delivery systems for improved antibacterial activity of cefixime against S. aureus and E. coli

28. September 2023

Cefixime (CEF) has numerous potential applications in the treatment of bacterial infections. However, due to its decreased cellular internalization, poor...

Polysorbates