DFE Pharma

Abstract The objective was to derive indications of the microstructure of lactose powder compacts was studied by small-angle and ultra...

Abstract We study the response of two twin-screw granulators of different barrel diameter to the variation of three process parameters...

Abstract The porosity of a pharmaceutical tablet influences liquid transport, disintegration and dissolution, rendering its monitoring and control crucial for...

Abstract Chlorothiazide (CTZ), a widely used thiazide diuretic, exhibits poor and variable oral bioavailability due to site-specific absorption and carrier-mediated...

Abstract The flowability and compressibility of powders during tableting are crucial for determining the quality of pharmaceutical products. Although silicon...

Abstract Since the FDA approval of the first nanodrug Doxil® in 1995, twenty subsequent liposome-and lipid nanoparticle (LNP) based drugs...

This poster was presented at the ECP 2025 in Porto   A proof of concept with wet extrusion Introduction Veterinary...

The effect of binder types on the granule properties and tablet quality for high shear wet granulation and tableting (HSWG-T)...

The mixing of ductile lubricant particles is known to have several negative effects on tablet properties, such as decreased hardness...

Purpose Understanding batch-to-batch variation of excipients and correlating this to process performance is a key concept of Quality-by-Design for pharmaceutical...