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Introduction High-drug-loaded tablets and capsules are desirable and are manufactured using granulation as an additional step. Replacing batch wet granulation...

Abstract Toxicological studies are a part of the drug development process and the preclinical stages, for which suitable vehicles ensuring...

Loading poorly soluble active pharmaceutical ingredients (API) into mesoporous silica can enable API stabilization in non-crystalline form, which leads to...

Abstract Using microcrystalline cellulose (MCC) with plastic behaviour and calcium phosphate anhydrous (CaHPO4) with brittle behaviour under compaction is very...

The pharmaceutical industry is paying more and more attention to hot-melt extrusion (HME), but this technology's promise for creating solid...

Flurbiprofen (FBP), a nonsteroidal anti-inflammatory drug (NSAID), is commonly used to treat the pain of rheumatoid arthritis, but in prolonged...

Abstract Drug loading into mesoporous carriers may help to improve the dissolution of poorly aqueous-soluble drugs. However, both preparation method...

In order to overcome the poor water solubility and instability of thymol to enhance its bioavailability, mesoporous silica nanoparticles (MSNPs:...

Background Subcutaneous injection of biopharmaceutical agents or microparticles is challenging due to issues with low injection efficiency and high residual...

In the present research, an attempt was made to optimize the blends of different carriers Neusilin US2, Avicel PH101, and...