Coating monitoring of pediatric minitablets using Optical Coherence Tomography (OCT)

1. October 2025

This poster was presented by RCPE, MERCK, TU Graz, Phyllon and hhu at the EuPFI conference 2025 in Bordeaux: Introduction...

Technical and regulatory perspective on acid stage dissolution assessed via optical coherence tomography (Part 1: Release Scenario)

22. September 2025

Abstract Enteric coating ensures a targeted release of active pharmaceutical ingredients (APIs) by protecting them from premature dissolution in the...

In-line porosity and hardness monitoring of tablets by means of optical coherence tomography

22. October 2024

In-line monitoring of critical quality attributes (CQAs) during a tableting process is an essential step toward a real-time release strategy....

In-situ monitoring of in vitro drug release processes in tablets using optical coherence tomography

10. July 2024

Film-coated modified-release tablets are an important dosage form amenable to targeted, controlled, or delayed drug release in the specific region...

Extending the Use of Optical Coherence Tomography to Scattering Coatings Containing Pigments

26. January 2024

Coating thickness is a critical quality attribute of many coated tablets. Functional coatings ensure correct drug release kinetics or protection...

An Integrated Real-time Monitoring and Statistical Process Control Approach for Coating Process and Product Quality via In-line Optical Coherence Tomography

1. December 2023

Abstract Purpose The thickness and other quality aspects of pharmaceutical coatings can be significantly impacted by coating process conditions. Under...

Optical Methods for Non-Invasive Determination of Skin Penetration: Current Trends, Advances, Possibilities, Prospects, and Translation into In Vivo Human Studies

16. September 2023

Information on the penetration depth, pathways, metabolization, storage of vehicles, active pharmaceutical ingredients (APIs), and functional cosmetic ingredients (FCIs) of...

Prediction of dissolution performance of uncoated solid oral dosage forms via optical coherence tomography

18. July 2023

Abstract Real-time prediction of the dissolution behavior of solid oral dosage forms is an important research topic. Although methods such...

Optical Coherence Tomography as a novel tool for non-invasive membrane thickness monitoring of co-extruded drug-delivery systems

8. July 2023

Abstract Co-extruded core-membrane formulations have been extensively explored as long-acting subcutaneous implants or vaginal inserts, guaranteeing zero-order release. Although the...

Ultra-High-Resolution Optical Coherence Tomography for the investigation of thin multilayered pharmaceutical coatings

10. June 2023

Optical Coherence Tomography (OCT) has recently gained attention as a promising technology for in-line monitoring of pharmaceutical film-coating processes for...

Phyllon