Abstract The research study provides an insight into different manufacturers' microcrystalline celluloses (MCC) thorough characterization, comprising determination of morphology, PSD, percentage crystallinity, surface area, true density,…

Abstract Improving the manufacturability of drug formulations via direct compression has been of great interest for the pharmaceutical industry. Selecting excipients plays a vital role in obtaining a high-quality product without the wet…

Abstract The objective was to derive indications of the microstructure of lactose powder compacts was studied by small-angle and ultra small-angle X-ray scattering experiments (SAXS/USAXS). Measurements were performed on a series of…

This poster was presented at the ECP 2025 in Porto Introduction The following polymorphic forms of lactose exist: α-Lactose Monohydrate (α-LMH), α-Lactose Anhydrous (α-LA) stable, α-LA unstable, β-Lactose Anhydrous (ß-LA) and…

Lactose is recovered from whey through crystallization process, where a concentrated supersaturated solution is cooled to crystallize the lactose, leaving the impurities in the mother liquor. Designing this process requires considerations…

Lactose is used as a diluent or a binder depending on the galenics in the pharmaceutical industry. It has been used as an excipient for over 100 years particularly in Oral Solid Dose in which it is present in more than 60% of them. Thus…

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Abstract Background/Objectives: The aim of the present study was to develop lactose-free formulations of rivaroxaban, a novel oral anticoagulant used for the treatment and prevention of blood clotting. As a BCS Class II drug, rivaroxaban…

Abstract Curcumin, a bioactive compound derived from turmeric, possesses numerous pharmaceutical properties; however, its poor aqueous solubility and permeability result in low bioavailability. This study aims to develop a solid…

In this study, binary powder blends of acetaminophen (ACAM) and α-lactose monohydrate (LM) at different mixing ratios, with fine, medium-size, and coarse particles are investigated with a new two-chamber setup (TCS) to assess dustiness. The…