DRcaps® Capsules Achieve Delayed Release Properties for Nutritional Ingredients in Human Clinical Study

Probiotics and enzymes are sensitive to acid and run the risk of being rendered less effective while crossing the low pH of the stomach on their way to the intestinal tract. That is why, Capsugel® performed a gamma-scintigraphy study that confirms delayed release properties of Capsugel® DRcaps™ capsules in human subjects.

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Introducing DRcaps Capsules
DRcaps® capsule, was developed to effectively address all of the various challenges and shortcomings of delivering acid-sensitive ingredients. The revolutionary dosage form offers unique polymer properties formulated within the capsule itself to slow the capsule opening after swallowing without adding coating ingredients that increase manufacturing time and costs. With moisture content of 4% to 6% in 50% relative humidity, low moisture DRcaps capsules inherently enhance stability for moisture-sensitive probiotics. The innovative polymer properties also mask the taste and odor of ingredients; therefore, by protecting against early disintegration, DRcaps capsules actually reduce the potential for unpleasant odors, aftertaste and reflux from supplements. In particular, the unique polymer properties were designed to resist acid in order to protect nutritional ingredients from full release and disintegration in the stomach and allow for complete dissolution in the intestine.
With moisture content of 4% to 6% in 50% relative humidity, low moisture DRcaps capsules inherently enhance stability for moisture-sensitive probiotics.